[HTML][HTML] Diet and the microbiota–gut–brain axis: sowing the seeds of good mental health

K Berding, K Vlckova, W Marx, H Schellekens… - Advances in …, 2021 - Elsevier
Over the past decade, the gut microbiota has emerged as a key component in regulating
brain processes and behavior. Diet is one of the major factors involved in shaping the gut …

Discovering multifaceted role of vanillic acid beyond flavours: Nutraceutical and therapeutic potential

J Kaur, M Gulati, SK Singh, G Kuppusamy… - Trends in Food Science …, 2022 - Elsevier
Background Vanillic acid is a phenolic compound, found in various dietary sources and
medicinal plants. Apart from its extraction from these biological sources, it is also …

Nrf2: a dark horse in Alzheimer's disease treatment

A Osama, J Zhang, J Yao, X Yao, J Fang - Ageing research reviews, 2020 - Elsevier
Abstract Alzheimer's disease (AD), an age-dependent neurodegenerative disorder, is the
main cause of dementia. Common hallmarks of AD include the amyloid β-peptide (Aβ) …

Shaping the Nrf2-ARE-related pathways in Alzheimer's and Parkinson's diseases

L Fão, SI Mota, AC Rego - Ageing Research Reviews, 2019 - Elsevier
A failure in redox homeostasis is a common hallmark of Alzheimer's Disease (AD) and
Parkinson's Disease (PD), two age-dependent neurodegenerative disorders (NDD), causing …

Natural compounds for Alzheimer's disease therapy: a systematic review of preclinical and clinical studies

S Andrade, MJ Ramalho, JA Loureiro… - International journal of …, 2019 - mdpi.com
Alzheimer's Disease (AD) is a neurodegenerative disorder related with the increase of age
and it is the main cause of dementia in the world. AD affects cognitive functions, such as …

Melatonin rescue oxidative stress-mediated neuroinflammation/neurodegeneration and memory impairment in scopolamine-induced amnesia mice model

T Muhammad, T Ali, M Ikram, A Khan, SI Alam… - Journal of Neuroimmune …, 2019 - Springer
Cognitive decline and memory impairment induced by oxidative brain damage are the
critical pathological hallmarks of Alzheimer's disease (AD). Based on the potential …

Hesperetin confers neuroprotection by regulating Nrf2/TLR4/NF-κB signaling in an Aβ mouse model

M Ikram, T Muhammad, SU Rehman, A Khan… - Molecular …, 2019 - Springer
Hesperetin is a bioactive flavonoid in the body, produced from hesperidin. No
comprehensive studies have shown its protective effects in neurodegenerative disorders …

Deciphering the Potential Neuroprotective Effects of Luteolin against Aβ142-Induced Alzheimer's Disease

S Ahmad, MH Jo, M Ikram, A Khan, MO Kim - International Journal of …, 2021 - mdpi.com
The current study was undertaken to unveil the protective effects of Luteolin, a natural
flavonoid, against amyloid-beta (Aβ1–42)-induced neuroinflammation, amyloidogenesis …

The present and future of pharmacotherapy of Alzheimer's disease: A comprehensive review

A Anand, AA Patience, N Sharma, N Khurana - European journal of …, 2017 - Elsevier
Alzheimer's disease (AD) is a generalized term used for the loss in memory and other
intellectual abilities on levels serious enough to interfere with daily life. It accounts for 60 …

Anthocyanins and their metabolites as therapeutic agents for neurodegenerative disease

AN Winter, PC Bickford - Antioxidants, 2019 - mdpi.com
Neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis (ALS), are characterized by the death of neurons within specific …