Pesticides are important chemicals or biological agents that deter or kill pests. The use of
pesticides has continued to increase as it is still considered the most effective method to …

Pesticides are unique environmental contaminants that are specifically introduced into the
environment to control pests, often by killing them. Although pesticide application serves …

Neurodegenerative diseases including Alzheimer (AD) and Parkinson (PD) have attracted
attention in last decades due to their high incidence worldwide. The etiology of these …

The etiology of most neurodegenerative disorders is multifactorial and consists of an
interaction between environmental factors and genetic predisposition. The role of pesticide …

Among age-related neurodegenerative diseases, Parkinson's disease (PD) represents the
best example for which oxidative stress has been strongly implicated. The etiology of PD …

Environmental factors have been shown to contribute to the incidence of Parkinson's
disease (PD). Pesticides, which represent one of the primary classes of environmental …

Pesticide exposure has been implicated in the etiopathogenesis of Parkinson's disease
(PD); in particular, the organochlorine insecticide dieldrin is believed to be associated with …

6-Hydroxydopamine is a neurotoxin commonly used to lesion dopaminergic pathways and
generate experimental models for Parkinson disease, however, the cellular mechanism of 6 …

Humans are routinely exposed to a vast array of environmental neurotoxicants, including
pesticides, endocrine disrupters, and heavy metals. The long-term consequences of …

We recently demonstrated that protein kinase Cδ (PKCδ), an important member of the novel
PKC family, is a key oxidative stress-sensitive kinase that can be activated by caspase-3 …