Hypothalamic control of interoceptive hunger

JN Siemian, MA Arenivar, S Sarsfield, Y Aponte - Current Biology, 2021 - cell.com
While energy balance is critical to survival, many factors influence food intake beyond
caloric need or" hunger." Despite this, some neurons that drive feeding in mice are routinely …

The role of Beta-endorphin in food deprivation-mediated increases in food intake and binge-eating

L Tolentino, A Iqbal, S Rahman, K Lutfy - Brain Sciences, 2023 - mdpi.com
Food deprivation and binge eating represent significant public health concerns. Previous
studies have implicated that hypothalamic opioids are affected following food deprivation …

Effect of combination of peripheral oxytocin and naltrexone at subthreshold doses on food intake, body weight and feeding-related brain gene expression in male rats

MA Head, AS Levine, DG Christian, A Klockars… - Physiology & …, 2021 - Elsevier
In a recent case report involving a male with hypothalamic obesity, concurrent administration
of oxytocin (OT) and an opioid receptor antagonist, naltrexone (NTX), synergistically affected …

Acute Hypophagia and Changes in c-Fos Immunoreactivity in Adolescent Rats Treated with Low Doses of Oxytocin and Naltrexone

MA Head, LK McColl, A Klockars, AS Levine… - Journal of Clinical …, 2021 - mdpi.com
A recent case report has shown that an adjunctive oxytocin+ naltrexone (OT+ NTX)
treatment promoted more robust hypophagia and body weight reduction than OT alone in an …

Behavioral plasticity: Role of neuropeptides in shaping feeding responses

AS Levine, DC Jewett, CM Kotz, PK Olszewski - Appetite, 2022 - Elsevier
Behavioral plasticity refers to changes occurring due to external influences on an organism,
including adaptation, learning, memory and enduring influences from early life experience …

Anorexigenic effects of naltrexone in rats

DSN Keembiya Liyanagamage - 2023 - researchcommons.waikato.ac.nz
The accessibility of cheap, palatable, and caloric food in the industrialized world has shifted
the primary drive of eating behavior from hunger to pleasure; this change has played a …

Oxytocin as a pharmacological tool to curb overeating: Exploring synergy with opioid receptor blockade

MA Head - 2021 - researchcommons.waikato.ac.nz
The key factors shaping consumption involve a feeling of hunger (determines search for
calories), satiation (underpins termination of ingestive behaviour), and reward (adjusts …