High-resolution Slide-seqV2 spatial transcriptomics enables discovery of disease-specific cell neighborhoods and pathways

JL Marshall, T Noel, QS Wang, H Chen, E Murray… - Iscience, 2022 - cell.com
High-resolution spatial transcriptomics enables mapping of RNA expression directly from
intact tissue sections; however, its utility for the elucidation of disease processes and …

Inhibition of Renin Expression Is Regulated by an Epigenetic Switch From an Active to a Poised State

JP Smith, R Paxton, S Medrano, NC Sheffield… - …, 2024 - ahajournals.org
BACKGROUND: Renin-expressing cells are myoendocrine cells crucial for the maintenance
of homeostasis. Renin is regulated by cAMP, p300 (histone acetyltransferase p300)/CBP …

Differences in Immunohistochemical and Ultrastructural Features between Podocytes and Parietal Epithelial Cells (PECs) Are Observed in Developing, Healthy …

M Ogorevc, I Kosovic, N Filipovic, I Bocina… - International journal of …, 2022 - mdpi.com
During human kidney development, cells of the proximal nephron gradually differentiate into
podocytes and parietal epithelial cells (PECs). Podocytes are terminally differentiated cells …

Expression of pannexin 1 in the human kidney during embryonal, early fetal and postnatal development and its prognostic significance in diabetic nephropathy

I Jeličić, K Vukojević, A Racetin, D Čarić… - Biomedicines, 2022 - mdpi.com
Pannexins are transmembrane glycoproteins that constitute channels involved in purinergic
signaling through ATP release from cells in various physiological and pathological …

Connexin Expression Is Altered in Liver Development of Yotari (dab1 -/-) Mice

V Paštar, M Lozić, N Kelam, N Filipović… - International journal of …, 2021 - mdpi.com
Disabled-1 (Dab1) protein is an intracellular adaptor of reelin signaling required for prenatal
neuronal migration, as well as postnatal neurotransmission, memory formation and synaptic …

Expression pattern of inos, bcl-2 and mmp-9 in the hip synovium tissue of patients with osteoarthritis

D Caric, S Zekic Tomas, N Filipovic, V Soljic… - International journal of …, 2021 - mdpi.com
Hip osteoarthritis (HOA) is characterized by degradation of the cartilage and synovitis.
However, the pathohistological effects of synovial tissue inflammation on HOA are not clear …

Expression Pattern of 5-HT (Serotonin) Receptors during Normal Development of the Human Spinal Cord and Ganglia and in Fetus with Cervical Spina Bifida

H Punda, S Mardesic, N Filipovic, I Kosovic… - International journal of …, 2021 - mdpi.com
The expression of 5-HT (serotonin) receptors (sr) was analyzed in the spinal cord and
ganglia of 15 human conceptuses (5–10-weeks), and in the 9-week fetus with spina bifida …

Sex-specific effects of metformin and liraglutide on renal pathology and expression of connexin 45 and pannexin 1 following long-term high-fat high-sugar diet

M Luetić, G Kretzschmar, M Grobe, L Jerčić, I Bota… - Acta histochemica, 2021 - Elsevier
The comparative effects of the two commonly used antidiabetic drugs metformin and
liraglutide on renal pathology and expression of connexin 45 (Cx45) and pannexin 1 …

Connexin 43 is localized in gizzard smooth muscle cells during chicken development

K Tokunaga, S Akimoto, M Aiba… - The Journal of Poultry …, 2022 - jstage.jst.go.jp
Smooth muscle cells are widely distributed in the digestive organs of chickens. They exist as
single cells, but adhere to each other to function synchronously. In this study, the expression …

Клинические аспекты экспрессии коннексинов 40, 37, 43, 45 в эмбриональной и взрослой почках

ЕЮ Шаповалова, ЛА Кутузова… - Журнал анатомии и …, 2023 - anatomy.elpub.ru
Аннотация В настоящее время обсуждения специфической экспрессии отдельных
форм коннексинов (Сх) в рениновом аппарате эмбриональной и взрослой почек …