The ability to quantify levels of target analytes in biological samples accurately and precisely
in biomonitoring involves the use of highly sensitive and selective instrumentation such as …

Background: Mass spectrometry (MS) is being introduced into a large number of clinical
laboratories. It provides specificity because of its ability to monitor selected mass ions …

The review discusses the pitfalls of the matrix effect in mass spectrometry detection
hyphenated to liquid chromatography separation. Matrix effect heavily influences both …

The primary aim of “omic” technologies is the nontargeted identification of all gene products
(transcripts, proteins, and metabolites) present in a specific biological sample. By their …

Recent progress in metabolomics and the development of increasingly sensitive analytical
techniques have renewed interest in global profiling, ie, semiquantitative monitoring of all …

Advanced functional genomic tools now allow the parallel and high-throughput analyses of
gene and protein expression. Although this information is crucial to our understanding of …

A new strategy has been developed for characterization of the most challenging complex
mixtures to date, using a combination of custom-designed experiments and a new data pre …

Although the exposure assessment of chemicals of emerging concern (CECs) has taken a
decisive step forward through advances in (bio) informatics, statistics, and the development …

Proteins comprise a majority of the dry weight of a cell, rendering them a major target for
oxidative modification. Oxidation of proteins can result in significant alterations in protein …

In recent years, pharmaceutical and personal care products (PPCPs) have been detected in
diverse environments (including groundwater, river water, and municipal wastewater). In …