L-asparaginase as a critical component to combat Acute Lymphoblastic Leukaemia (ALL): A novel approach to target ALL

U Ali, M Naveed, A Ullah, K Ali, SA Shah… - European journal of …, 2016 - Elsevier
L-asparaginase, an anti-leukaemic drug that has been approved for clinical use for many
years in the treatment of childhood Acute Lymphoblastic Leukaemia (ALL), is obtained from …

Immobilization of l-Asparaginase on Carrier Materials: A Comprehensive Review

A Ulu, B Ates - Bioconjugate chemistry, 2017 - ACS Publications
There are two major applications of l-asparaginase (L-ASNase): leukemia therapy and the
food industry. Especially, its chemotherapeutic effect has attracted interest from the scientific …

Immobilization of L-asparaginase on aspartic acid functionalized graphene oxide nanosheet: enzyme kinetics and stability studies

M Monajati, S Borandeh, A Hesami, D Mansouri… - Chemical Engineering …, 2018 - Elsevier
There is an increasing interest in using l-asparaginase in medical fields and food processing
industries. Enzyme immobilization is an attractive field to improve l-asparaginase activity …

Ultrasound-propelled nanowire motors enhance asparaginase enzymatic activity against cancer cells

M Uygun, B Jurado-Sanchez, DA Uygun, VV Singh… - Nanoscale, 2017 - pubs.rsc.org
Ultrasound-(US) propelled nanowires consisting of Au/Ni/Au/PEDOT-PPy-COOH segments
are modified with asparaginase enzyme and applied as an effective anti-cancer agent. After …

Magnetic Fe3O4@MCM-41 core–shell nanoparticles functionalized with thiol silane for efficient l-asparaginase immobilization

A Ulu, SAA Noma, S Koytepe, B Ates - Artificial cells, nanomedicine …, 2018 - Taylor & Francis
Abstract l-Asparaginase (l-ASNase) is a vital enzyme for medical treatment and food
industry. Here, we assessed the use of Fe3O4@ Mobil Composition of Matter No. 41 (MCM …

Synthesis and characterization of biodegradable pHEMA-starch composites for immobilization of L-asparaginase

A Ulu, S Koytepe, B Ates - Polymer Bulletin, 2016 - Springer
Abstract In this paper, poly (2-hydroxyethyl methacrylate)(pHEMA) and poly (2-hydroxyethyl
methacrylate)-starch (pHEMA-S) composites were prepared from 2-hydroxyethyl …

Optimization, purification and characterization of recombinant L-asparaginase II in Escherichia coli

TTH Nguyen, CT Nguyen, TS Le Nguyen… - African Journal of …, 2016 - ajol.info
We studied optimal L-asparaginase sequence from GenBank accession number X12746
encoding for Lasparaginase from Erwinia chrysanthemi NCPPB1125. The expression level …

Optimization of L-asparaginase activity of Actinobacteria isolated from Guaviare river sediments in Colombia

M Morales-Gonzalez, BS Martinez… - Tropical Journal of …, 2018 - ajol.info
Purpose: To optimize the L-asparaginase activity of Actinobacteria isolated from Guaviare
river sediments in Colombia. Methods: Actinobacterial strains were evaluated for their L …

A preliminary study on L-asparaginase from mangrove detritus-derived fungi and its application in plant growth promotion

VS Damare, KG Kajawadekar - 2020 - irgu.unigoa.ac.in
L-asparaginase enzyme has wide applications in medicine, food industry and developing
biosensors. The present study was carried out to investigate the plant growth-promoting …

[PDF][PDF] ALKALINE PHOSPHATASE AND L-ASPERGENSES ENZYMIC ACTIVITY ASSESSMENT IN DIFFERENT PLANTS

LS Al-Taweel, GA Alwan - Plant Archives, 2019 - plantarchives.org
In order to study the activity of alkaline phosphatase and L-asparaginase enzymes in the
plant, eight different sites in some of their chemical, physical and biochemical characteristics …