Pathogenicity and virulence of human adenovirus F41: possible links to severe hepatitis in children
RJ Grand - Virulence, 2023 - Taylor & Francis
Over 100 human adenoviruses (HAdVs) have been isolated and allocated to seven species,
AG. Species F comprises two members-HAdV-F40 and HAdV-F41. As their primary site of …
AG. Species F comprises two members-HAdV-F40 and HAdV-F41. As their primary site of …
[HTML][HTML] Cullin E3 ligases and their rewiring by viral factors
The ability of viruses to subvert host pathways is central in disease pathogenesis. Over the
past decade, a critical role for the Ubiquitin Proteasome System (UPS) in counteracting host …
past decade, a critical role for the Ubiquitin Proteasome System (UPS) in counteracting host …
ORF10–Cullin-2–ZYG11B complex is not required for SARS-CoV-2 infection
In order to understand the transmission and virulence of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), it is necessary to understand the functions of each of the gene …
coronavirus 2 (SARS-CoV-2), it is necessary to understand the functions of each of the gene …
The role of cullin 5-containing ubiquitin ligases
F Okumura, A Joo-Okumura, K Nakatsukasa, T Kamura - Cell division, 2016 - Springer
The suppressor of cytokine signaling (SOCS) box consists of the BC box and the cullin 5
(Cul5) box, which interact with Elongin BC and Cul5, respectively. SOCS box-containing …
(Cul5) box, which interact with Elongin BC and Cul5, respectively. SOCS box-containing …
The structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functions
W Cai, H Yang - Cell division, 2016 - Springer
Abstract Background Cullin-RING E3 ubiquitin ligase complexes play a central role in
targeting cellular proteins for ubiquitination-dependent protein turnover through 26S …
targeting cellular proteins for ubiquitination-dependent protein turnover through 26S …
[HTML][HTML] A comparative review of adenovirus A12 and C5 oncogenes
LD Bertzbach, WH Ip, K von Stromberg… - Current Opinion in …, 2024 - Elsevier
Oncogenic viruses contribute to 15% of global human cancers. To achieve that, virus-
encoded oncoproteins deregulate cellular transcription, antagonize common cellular …
encoded oncoproteins deregulate cellular transcription, antagonize common cellular …
Using the E4orf6-based E3 ubiquitin ligase as a tool to analyze the evolution of adenoviruses
T Gilson, P Blanchette, MZ Ballmann, T Papp… - Journal of …, 2016 - Am Soc Microbiol
ABSTRACT E4orf6 proteins from all human adenoviruses form Cullin-based ubiquitin ligase
complexes that, in association with E1B55K, target cellular proteins for degradation. While …
complexes that, in association with E1B55K, target cellular proteins for degradation. While …
The human adenovirus type 5 E4orf6/E1B55K E3 ubiquitin ligase complex enhances E1A functional activity
F Dallaire, S Schreiner, GE Blair, T Dobner… - MSphere, 2016 - Am Soc Microbiol
ABSTRACT Human adenovirus (Ad) E1A proteins have long been known as the central
regulators of virus infection as well as the major source of adenovirus oncogenic potential …
regulators of virus infection as well as the major source of adenovirus oncogenic potential …
The human adenovirus type 5 E4orf6/E1B55K E3 ubiquitin ligase complex can mimic E1A effects on E2F
F Dallaire, S Schreiner, GE Blair, T Dobner, PE Branton… - Msphere, 2016 - Am Soc Microbiol
The human adenovirus E4orf6/E1B55K E3 ubiquitin ligase is well known to promote viral
replication by degrading an increasing number of cellular proteins that inhibit the efficient …
replication by degrading an increasing number of cellular proteins that inhibit the efficient …