Vaccines for COVID-19

JS Tregoning, ES Brown… - Clinical & …, 2020 - academic.oup.com
Since the emergence of COVID-19, caused by the SARS-CoV-2 virus at the end of 2019,
there has been an explosion of vaccine development. By 24 September 2020, a staggering …

Viruses and autoimmunity: a review on the potential interaction and molecular mechanisms

MK Smatti, FS Cyprian, GK Nasrallah, AA Al Thani… - Viruses, 2019 - mdpi.com
For a long time, viruses have been shown to modify the clinical picture of several
autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus …

Insights in ChAdOx1 nCoV-19 vaccine-induced immune thrombotic thrombocytopenia

A Greinacher, K Selleng, R Palankar… - Blood, The Journal …, 2021 - ashpublications.org
Abstract SARS-CoV-2 vaccine ChAdOx1 nCoV-19 (AstraZeneca) causes a thromboembolic
complication termed vaccine-induced immune thrombotic thrombocytopenia (VITT). Using …

Narcolepsy—clinical spectrum, aetiopathophysiology, diagnosis and treatment

CLA Bassetti, A Adamantidis, D Burdakov… - Nature Reviews …, 2019 - nature.com
Narcolepsy is a rare brain disorder that reflects a selective loss or dysfunction of orexin (also
known as hypocretin) neurons of the lateral hypothalamus. Narcolepsy type 1 (NT1) is …

[HTML][HTML] Molecular mimicry and autoimmunity

M Rojas, P Restrepo-Jiménez, DM Monsalve… - Journal of …, 2018 - Elsevier
Molecular mimicry is one of the leading mechanisms by which infectious or chemical agents
may induce autoimmunity. It occurs when similarities between foreign and self-peptides …

The immunopathogenesis of narcolepsy type 1

RS Liblau, D Latorre, BR Kornum… - Nature Reviews …, 2024 - nature.com
Abstract Narcolepsy type 1 (NT1) is a chronic sleep disorder resulting from the loss of a
small population of hypothalamic neurons that produce wake-promoting hypocretin (HCRT; …

Vaccine-induced autoimmunity: the role of molecular mimicry and immune crossreaction

Y Segal, Y Shoenfeld - Cellular & molecular immunology, 2018 - nature.com
Since the early 1800s vaccines have saved numerous lives by preventing lethal infections.
However, during the past two decades, there has been growing awareness of possible …

[HTML][HTML] Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity

J Lyons-Weiler - Journal of translational autoimmunity, 2020 - Elsevier
Homology between human and viral proteins is an established factor in viral-or vaccine-
induced autoimmunity. Failure of SARS and MERS vaccines in animal trials involved …

T cells in patients with narcolepsy target self-antigens of hypocretin neurons

D Latorre, U Kallweit, E Armentani, M Foglierini, F Mele… - Nature, 2018 - nature.com
Narcolepsy is a chronic sleep disorder caused by the loss of neurons that produce
hypocretin. The close association with HLA-DQB1* 06: 02, evidence for immune …

Autoimmune and rheumatic musculoskeletal diseases as a consequence of SARS-CoV-2 infection and its treatment

S Shah, D Danda, C Kavadichanda, S Das… - Rheumatology …, 2020 - Springer
Abstract The coronavirus disease-2019 (COVID-19) pandemic is likely to pose new
challenges to the rheumatology community in the near and distant future. Some of the …