Acute kidney injury (AKI) is the leading cause of nephrology consultation and is associated
with high mortality rates. The primary causes of AKI include ischemia, hypoxia or …

The development of the human kidney is a complex process that requires interactions
between epithelial and mesenchymal cells, eventually leading to the coordinated growth …

The homeobox gene Emx2 is a mouse homologue of a Drosophila head gap gene empty
spiracles (ems) and is essential for the development of dorsal telencephalon (Development …

Metanephric mesenchyme gives rise to both the epithelial cells of the nephron and the
stromal cells of the mature kidney. The function of the stroma. in kidney morphogenesis is …

Hoxa 11 is a murine Abdominal-B-type homeobox gene. The structure of this gene is
presented, including genomic and cDNA sequence. The cDNA includes the complete open …

Development of the metanephric kidney requires the concerted interaction of two tissues, the
epithelium of the ureteric duct and the metanephric mesenchyme. Signals from the ureter …

Laminins are major components of all basement membranes. They are a diverse group of
α/β/γ heterotrimers formed from five α, three β, and three γ chains. Laminin α5 is a widely …

The murine dominant negative helix-loop-helix (dnHLH) proteins inhibit the activities of
bHLH transcription factors in diverse cell lineages (Benezra et al. 119901 Cell 61: 49-59; …

Development of the metanephric kidney is an experimental model system to analyze
interactions between mesenchymal and epithelial cells and mesenchymal-epithelial …

TRANSFAC is a database on transcription factors, their genomic binding sites and DNA-
binding profiles. In addition to being updated and extended by new features, it has been …