Long-term immunosuppression management: opportunities and uncertainties

D Wojciechowski, A Wiseman - … Journal of the American Society of …, 2021 - journals.lww.com
The long-term management of maintenance immunosuppression in kidney transplant
recipients remains complex. The vast majority of patients are treated with the calcineurin …

Diagnosis and prevention of chronic kidney allograft loss

BJ Nankivell, DRJ Kuypers - The Lancet, 2011 - thelancet.com
Kidney transplantation is the best possible treatment for many patients with end-stage renal
failure, but progressive dysfunction and eventual allograft loss with return to dialysis is …

[HTML][HTML] Each additional hour of cold ischemia time significantly increases the risk of graft failure and mortality following renal transplantation

A Debout, Y Foucher, K Trébern-Launay, C Legendre… - Kidney international, 2015 - Elsevier
Although cold ischemia time has been widely studied in renal transplantation area, there is
no consensus on its precise relationship with the transplantation outcomes. To study this, we …

Consensus recommendations for use of maintenance immunosuppression in solid organ transplantation: Endorsed by the American College of Clinical Pharmacy …

J Nelson, N Alvey, L Bowman, J Schulte… - … : The Journal of …, 2022 - Wiley Online Library
Advances in maintenance immunosuppression over the past three decades have improved
solid organ transplantation outcomes dramatically. Uninterrupted access to …

A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation

P Khatri, S Roedder, N Kimura, K De Vusser… - Journal of Experimental …, 2013 - rupress.org
Using meta-analysis of eight independent transplant datasets (236 graft biopsy samples)
from four organs, we identified a common rejection module (CRM) consisting of 11 genes …

Pharmacology and toxicology of mycophenolate in organ transplant recipients: an update

CE Staatz, SE Tett - Archives of toxicology, 2014 - Springer
This review aims to provide an update of the literature on the pharmacology and toxicology
of mycophenolate in solid organ transplant recipients. Mycophenolate is now the …

Risk factors associated with post–kidney transplant malignancies: an article from the Cancer-Kidney International Network

B Sprangers, V Nair, V Launay-Vacher… - Clinical Kidney …, 2018 - academic.oup.com
In kidney transplant recipients, cancer is one of the leading causes of death with a
functioning graft beyond the first year of kidney transplantation, and malignancies account …

Malignancy after renal transplantation: the role of immunosuppression

I Rama, JM Grinyó - Nature Reviews Nephrology, 2010 - nature.com
Outcomes of kidney transplantation, in terms of graft and patient survival, have improved
over the past few decades, partly as a result of the introduction of new immunosuppressive …

Mycophenolic acid versus azathioprine as primary immunosuppression for kidney transplant recipients

M Wagner, AK Earley, AC Webster… - Cochrane Database …, 2015 - cochranelibrary.com
Background Modern immunosuppressive regimens after kidney transplantation usually use
a combination of two or three agents of different classes to prevent rejection and maintain …

Epidemiology, risk factors and outcomes of invasive aspergillosis in solid organ transplant recipients in the Swiss Transplant Cohort Study

D Neofytos, O Chatzis, D Nasioudis… - Transplant infectious …, 2018 - Wiley Online Library
Background There is lack of recent multicenter epidemiological data on invasive
aspergillosis (IA) among solid organ transplant recipient (SOT r) in the mold‐acting …