Understanding sources of variation to improve the reproducibility of radiomics

B Zhao - Frontiers in oncology, 2021 - frontiersin.org
Radiomics is the method of choice for investigating the association between cancer imaging
phenotype, cancer genotype and clinical outcome prediction in the era of precision …

Artificial intelligence in lung cancer imaging: unfolding the future

M Cellina, M Cè, G Irmici, V Ascenti, N Khenkina… - Diagnostics, 2022 - mdpi.com
Lung cancer is one of the malignancies with higher morbidity and mortality. Imaging plays
an essential role in each phase of lung cancer management, from detection to assessment …

Intrinsic dependencies of CT radiomic features on voxel size and number of gray levels

M Shafiq‐ul‐Hassan, GG Zhang, K Latifi… - Medical …, 2017 - Wiley Online Library
Purpose Many radiomics features were originally developed for non‐medical imaging
applications and therefore original assumptions may need to be reexamined. In this study …

Reproducibility of radiomics for deciphering tumor phenotype with imaging

B Zhao, Y Tan, WY Tsai, J Qi, C Xie, L Lu… - Scientific reports, 2016 - nature.com
Radiomics (radiogenomics) characterizes tumor phenotypes based on quantitative image
features derived from routine radiologic imaging to improve cancer diagnosis, prognosis …

[HTML][HTML] Radiomic features are associated with EGFR mutation status in lung adenocarcinomas

Y Liu, J Kim, Y Balagurunathan, Q Li, AL Garcia… - Clinical lung cancer, 2016 - Elsevier
Background In this study we retrospectively evaluated the capability of computed
tomography (CT)-based radiomic features to predict epidermal growth factor receptor …

CT radiogenomic characterization of EGFR, K-RAS, and ALK mutations in non-small cell lung cancer

S Rizzo, F Petrella, V Buscarino, F De Maria… - European …, 2016 - Springer
Objectives To assess the association between CT features and EGFR, ALK, KRAS mutations
in non-small cell lung cancer. Methods Patients undergoing chest CT and testing for the …

Identification of non–small cell lung cancer sensitive to systemic cancer therapies using radiomics

L Dercle, M Fronheiser, L Lu, S Du, W Hayes… - Clinical Cancer …, 2020 - AACR
Purpose: Using standard-of-care CT images obtained from patients with a diagnosis of non–
small cell lung cancer (NSCLC), we defined radiomics signatures predicting the sensitivity of …

Defining a radiomic response phenotype: a pilot study using targeted therapy in NSCLC

HJWL Aerts, P Grossmann, Y Tan, GR Oxnard… - Scientific reports, 2016 - nature.com
Medical imaging plays a fundamental role in oncology and drug development, by providing
a non-invasive method to visualize tumor phenotype. Radiomics can quantify this phenotype …

CT features associated with epidermal growth factor receptor mutation status in patients with lung adenocarcinoma

Y Liu, J Kim, F Qu, S Liu, H Wang, Y Balagurunathan… - Radiology, 2016 - pubs.rsna.org
Purpose To retrospectively identify the relationship between epidermal growth factor
receptor (EGFR) mutation status, predominant histologic subtype, and computed …

Non–small cell lung cancer radiogenomics map identifies relationships between molecular and imaging phenotypes with prognostic implications

M Zhou, A Leung, S Echegaray, A Gentles, JB Shrager… - Radiology, 2018 - pubs.rsna.org
Purpose To create a radiogenomic map linking computed tomographic (CT) image features
and gene expression profiles generated by RNA sequencing for patients with non–small cell …