The presence of N-heterocycles as an essential structural motif in a variety of biologically
active substances has stimulated the development of new strategies and technologies for …

The present article reviews published efforts to study acetylcholinesterase and
butyrylcholinesterase structure and function using computer-based modeling and simulation …

An efficient chemodivergent strategy for visible light photocatalysis is developed. In the
presence of a dicyanopyrazine-derived chromophore (DPZ) photocatalyst, aerobic …

Quinazolines are considered as a promising class of bioactive heterocyclic compounds with
broad properties. Particularly, the quinazoline scaffold has an impressive role in the design …

In this study, novel quinazolinone derivatives 7a-n were synthesized and evaluated against
metabolic enzymes including α-glycosidase, acetylcholinesterase, butyrylcholinesterase …

The site-selective modification of quinazolinone as a privileged bicyclic N-heterocycle is an
attractive topic in medicinal chemistry and material science. We herein report the ruthenium …

Acetylcholinesterase is an important biochemical enzyme in that it controls acetylcholine-
mediated neuronal transmission in the central nervous system, contains a unique structure …

Butyrylcholinesterase (BChE) is a promising target for the treatment of later stage cognitive
decline in Alzheimer's disease. A set of pseudo-irreversible BChE inhibitors with high …

Most of the precedent copper‐catalyzed trifluoromethylation reactions of unactivated
alkenes concern terminal alkenes, and these processes are terminated in elimination, or …

The enzyme butyrylcholinesterase (BChE) and the human cannabinoid receptor 2 (h CB2R)
represent promising targets for pharmacotherapy in the later stages of Alzheimer's disease …