Leptomeningeal metastasis from systemic cancer: review and update on management

N Wang, MS Bertalan, PK Brastianos - Cancer, 2018 - Wiley Online Library
Leptomeningeal metastasis is an uncommon and typically late complication of cancer with a
poor prognosis and limited treatment options. Diagnosis is often challenging, with …

Barriers to accrual and enrollment in brain tumor trials

EQ Lee, UN Chukwueke, SL Hervey-Jumper… - Neuro …, 2019 - academic.oup.com
Many factors contribute to the poor survival of malignant brain tumor patients, some of which
are not easily remedied. However, one contributor to the lack of progress that may be …

Magnetic resonance image features identify glioblastoma phenotypic subtypes with distinct molecular pathway activities

H Itakura, AS Achrol, LA Mitchell, JJ Loya… - Science translational …, 2015 - science.org
Glioblastoma (GBM) is the most common and highly lethal primary malignant brain tumor in
adults. There is a dire need for easily accessible, noninvasive biomarkers that can delineate …

Who counts in crises? The new geopolitics of international migration and refugee governance

W Allen, B Anderson, N Van Hear, M Sumption… - …, 2018 - Taylor & Francis
Recent migration 'crises' raise important geopolitical questions. Who is 'the migrant'that
contemporary politics are fixated on? How are answers to 'who counts as a …

Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: Safety and efficacy assessment

DA Bota, TH Taylor, DE Piccioni, CM Duma… - Journal of Experimental …, 2022 - Springer
Background Vaccine immunotherapy may improve survival in Glioblastoma (GBM). A
multicenter phase II trial was designed to determine:(1) the success rate of manufacturing …

Capsaicin induces redox imbalance and ferroptosis through ACSL4/GPx4 signaling pathways in U87-MG and U251 glioblastoma cells

C Hacioglu, F Kar - Metabolic Brain Disease, 2023 - Springer
Glioblastoma is one of the deadliest malignant gliomas. Capsaicin is a homovanillic acid
derivative that can show anti-cancer effects by regulating various signaling pathways. The …

Validation and development of a modified breast graded prognostic assessment as a tool for survival in patients with breast cancer and brain metastases

IM Subbiah, X Lei, JS Weinberg, EP Sulman… - Journal of Clinical …, 2015 - ascopubs.org
Purpose Several indices have been developed to predict overall survival (OS) in patients
with breast cancer with brain metastases, including the breast graded prognostic …

Brain metastasis from renal cell carcinoma: presentation, recurrence, and survival

B Shuch, JC La Rochelle, T Klatte… - … Journal of the …, 2008 - Wiley Online Library
BACKGROUND. Patients with renal cell carcinoma brain metastases (RCCBM) are
frequently excluded from trials and to the authors' knowledge no guidelines currently exist …

Molecular classification and therapeutic targets in ependymoma

T Larrew, BF Saway, SR Lowe, A Olar - Cancers, 2021 - mdpi.com
Simple Summary Molecular characterization of ependymoma has revolutionized its
categorization. This new molecular classification has implications particularly in targeted …

Anti-cancer auto-antibodies: Roles, applications and open issues

H de Jonge, L Iamele, M Maggi, G Pessino, C Scotti - Cancers, 2021 - mdpi.com
Simple Summary Cancer is one of the main causes of death worldwide and early detection
is crucial for effective treatment. Scientists have therefore focused on the identification of …