Sirtuin 3 (SIRT3), the nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase,
acts as a metabolic modulator mainly located in mitochondria via regulating the process of …

Abstract Sin3 associated protein 18 (SAP18) is an evolutionary conserved protein, originally
discovered in a complex with the transcriptional regulatory protein, Sin3. Subsequent …

Lymphoma is a cancer of the lymphoid cells that originated in matured B or T cells. The
bioactive natural compounds can efficiently treat this disease with lesser side effects. Thus …

The pyrimido-indole derivative UM171 promotes human Hematopoietic Stem Cells
Expansion (HSCE), but its impact on leukemia is not known. Herein, we show in a mouse …

Leukemia is responsible for a reason of death, globally. Even though there are several
treatment regimens available in the clinics against this disease, a perfect chemotherapeutic …

The dysregulation of alternative splicing (AS) is increasingly recognized as a pivotal player
in the pathogenesis, progression, and treatment resistance of B-cell acute lymphoblastic …

Lymphoma positions as the fifth most common cancer, in the world, reporting remarkable
deaths every year. Several promising strategies to counter this disease recently include …

Background Leukemia accounts for a large number of deaths, worldwide, every year.
Treating this ailment is always a challenging job. Recently, oncogenic miRNA leading to …

Molecular signal transduction networks, which conduct transcription at the G1 to S phase
transition of the eukaryotic cell division cycle have been identified in diverse taxa from …

Chronic myeloid leukemia (CML) accounts for a major cause of death in adult leukemia
patients due to mutations or other reasons for dysfunction in the ABL proto-oncogene. The …