Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology

DQ Huang, AG Singal, F Kanwal… - Nature Reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …

Epidemiology and surveillance for hepatocellular carcinoma: New trends

AG Singal, P Lampertico, P Nahon - Journal of hepatology, 2020 - Elsevier
The burden of hepatocellular carcinoma (HCC) is highest in East Asia and Africa, although
its incidence and mortality are rapidly rising in the United States and Europe. With the …

Blood-based biomarkers for hepatocellular carcinoma screening: Approaching the end of the ultrasound era?

ND Parikh, N Tayob, AG Singal - Journal of hepatology, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, in
part because of inadequate early detection strategies. Current recommendations for …

Surveillance for hepatocellular carcinoma: current best practice and future direction

F Kanwal, AG Singal - Gastroenterology, 2019 - Elsevier
Hepatocellular cancer (HCC) is the fourth leading cause of cancer-related deaths worldwide
and the fastest growing cause of cancer deaths in the United States. The overall prognosis …

Use of hepatocellular carcinoma surveillance in patients with cirrhosis: a systematic review and meta‐analysis

E Wolf, NE Rich, JA Marrero, ND Parikh… - Hepatology, 2021 - Wiley Online Library
Background and Aims Hepatocellular carcinoma (HCC) surveillance is associated with early
tumor detection and improved survival; however, it is often underused in clinical practice. We …

[PDF][PDF] Risk prediction models for post‐operative mortality in patients with cirrhosis

N Mahmud, Z Fricker, RA Hubbard, GN Ioannou… - …, 2021 - Wiley Online Library
Background and Aims Patients with cirrhosis are at increased risk of postoperative mortality.
Currently available tools to predict postoperative risk are suboptimally calibrated and do not …

[PDF][PDF] Incidence and mortality of acute‐on‐chronic liver failure using two definitions in patients with compensated cirrhosis

N Mahmud, DE Kaplan, TH Taddei, DS Goldberg - Hepatology, 2019 - Wiley Online Library
The term acute‐on‐chronic liver failure (ACLF) is intended to identify patients with chronic
liver disease who develop rapid deterioration of liver function and high short‐term mortality …

Artificial intelligence in gastroenterology and hepatology: how to advance clinical practice while ensuring health equity

E Uche-Anya, A Anyane-Yeboa, TM Berzin… - Gut, 2022 - gut.bmj.com
Artificial intelligence (AI) and machine learning (ML) systems are increasingly used in
medicine to improve clinical decision-making and healthcare delivery. In gastroenterology …

[PDF][PDF] An eastern hepatobiliary surgery hospital/portal vein tumor thrombus scoring system as an aid to decision making on hepatectomy for hepatocellular carcinoma …

XP Zhang, YZ Gao, ZH Chen, MS Chen, LQ Li… - …, 2019 - Wiley Online Library
Portal vein tumor thrombus (PVTT) is a significant poor prognostic factor for hepatocellular
carcinoma (HCC). Patients with PVTT limited to a first‐order branch of the main portal vein …

Serum biomarkers for the prediction of hepatocellular carcinoma

JD Debes, PA Romagnoli, J Prieto, M Arrese… - Cancers, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is a leading cause of global cancer death. Major etiologies
of HCC relate to chronic viral infections as well as metabolic conditions. The survival rate of …