Modulatory Activity of the Endocannabinoid System in the Development and Proliferation of Cells in the CNS

HA Ruiz-Contreras, A Santamaría… - Neurotoxicity …, 2022 - Springer
Abstract The Endocannabinoid System (ECS, also known as Endocannabinoidome) plays a
key role in the function of the Central Nervous System, though the participation of this system …

A systematic review of the complex effects of cannabinoids on cerebral and peripheral circulation in animal models

JS Richter, V Quenardelle, O Rouyer, JS Raul… - Frontiers in …, 2018 - frontiersin.org
While cannabis is perceived as a relatively safe drug by the public, accumulating clinical
data suggest detrimental cardiovascular effects of cannabinoids. Cannabis has been …

Cannabis microbiome sequencing reveals several mycotoxic fungi native to dispensary grade Cannabis flowers

K McKernan, J Spangler, L Zhang, V Tadigotla… - …, 2016 - pmc.ncbi.nlm.nih.gov
The Center for Disease Control estimates 128,000 people in the US are hospitalized
annually due to food borne illnesses. This has created a demand for food safety testing …

Connexin 43 hemichannel activity promoted by pro-inflammatory cytokines and high glucose alters endothelial cell function

JC Sáez, S Contreras-Duarte, GI Gómez… - Frontiers in …, 2018 - frontiersin.org
The present work was done to elucidate whether hemichannels of a cell line derived from
endothelial cells are affected by pro-inflammatory conditions (high glucose and IL-1β/TNF-α) …

Considerations for cannabinoids in perioperative care by anesthesiologists

K Laudanski, J Wain - Journal of Clinical Medicine, 2022 - mdpi.com
Increased usage of recreational and medically indicated cannabinoid compounds has been
an undeniable reality for anesthesiologists in recent years. These compounds' complicated …

Cannabis exposure as an interactive cardiovascular risk factor and accelerant of organismal ageing: a longitudinal study

AS Reece, A Norman, GK Hulse - BMJ open, 2016 - bmjopen.bmj.com
Objectives Many reports exist of the cardiovascular toxicity of smoked cannabis but none of
arterial stiffness measures or vascular age (VA). In view of its diverse toxicology, the …

Cannabinoid signalling inhibits sarcoplasmic Ca2+ release and regulates excitation–contraction coupling in mammalian skeletal muscle

T Oláh, D Bodnár, A Tóth, J Vincze… - The Journal of …, 2016 - Wiley Online Library
Key points Marijuana was found to cause muscle weakness, although the exact regulatory
role of its receptors (CB1 cannabinoid receptor; CB1R) in the excitation–contraction …

Cannabinoids and cardiovascular system

AI Bondarenko - Recent Advances in Cannabinoid Physiology and …, 2019 - Springer
Cannabinoids influence cardiovascular variables in health and disease via multiple
mechanisms. The chapter covers the impact of cannabinoids on cardiovascular function in …

Pharmacognosy and effects of cannabinoids in the vascular system

E Mensah, R Tabrizchi… - ACS Pharmacology & …, 2022 - ACS Publications
Understanding the pharmacodynamics of cannabinoids is an essential subject due to the
recent increasing global acceptance of cannabis and its derivation for recreational and …

Cannabinoids—A New Perspective in Adjuvant Therapy for Pulmonary Hypertension

A Krzyżewska, M Baranowska-Kuczko… - International Journal of …, 2021 - mdpi.com
Currently, no treatment can completely cure pulmonary hypertension (PH), which can lead to
right ventricular failure and, consequently, death. Therefore, searching for new therapies …