Nonenzymatic molecular modifications induced by reactive carbonyl species (RCS)
generated by peroxidation of membrane phospholipids acyl chains play a causal role in the …

Aging is a progressive and universal process originating endogenously that manifests
during postmaturational life. Available comparative evidence supporting the mitochondrial …

The present state of the mitochondrial free radical theory of aging is reviewed. Available
studies do not support the hypothesis that antioxidants control the rate of aging because:(a) …

The appearance of oxygen in the terrestrial atmosphere represented an important selective
pressure for ancestral living organisms and contributed toward setting up the pace of …

One of the challenges facing science/biology today is uncovering the molecular bases that
support and determine animal and human longevity. Nature, in offering a diversity of animal …

I have been involved in research on polyunsaturated fatty acids since 1964 and this review
is intended to cover some of the most important aspects of this work. Polyunsaturated fatty …

Lipids were determinants in the appearance and evolution of life. Recent studies disclose
the existence of a link between lipids and animal longevity. Findings from both comparative …

The most studied comparison of aging and maximum lifespan potential (MLSP) among
endotherms involves the 7-fold longevity difference between rats (MLSP 5y) and pigeons …

Free radical damage is considered a determinant factor in the rate of aging. Unsaturated
fatty acids are the tissue macromolecules that are most sensitive to oxidative damage …

Antioxidative, antidiabetes, antibacterial, anticancer and angiotensin-converting enzyme
(ACE) inhibitory activities of methanol extracts of dried persimmon, fresh persimmon and …