Solid lipid nanoparticles and nanostructured lipid carriers: emerging lipid based drug delivery systems

RK Shirodkar, L Kumar, S Mutalik, S Lewis - Pharmaceutical Chemistry …, 2019 - Springer
In the past decade, research in the area of nanodrug delivery has reached a new height with
the advent of lipid based nanodrug delivery systems. Lipids being biocompatible and …

[HTML][HTML] Current applications and prospects of nanoparticles for antifungal drug delivery

S Nami, A Aghebati-Maleki, L Aghebati-Maleki - EXCLI journal, 2021 - ncbi.nlm.nih.gov
Currently, the significance of fungi as human pathogens is not medically concealed in the
world. Consequently, suitable recognition and treatment of such infections are of great …

Voriconazole loaded nanostructured lipid carriers based topical delivery system: QbD based designing, characterization, in-vitro and ex-vivo evaluation

T Waghule, VK Rapalli, G Singhvi, P Manchanda… - Journal of drug delivery …, 2019 - Elsevier
Clinical investigation showed that voriconazole exhibits various adverse effects such as
nausea, vomiting, and other gastric disturbances. To overcome these associated side …

High-pressure homogenization techniques for nanoparticles

P Vinchhi, JK Patel, MM Patel - Emerging Technologies for Nanoparticle …, 2021 - Springer
High-pressure homogenization (HPH) has been employed for unit operations like
comminution, mixing, and stabilization of pharmaceutical solids and nanoparticles. With …

Striking back against fungal infections: The utilization of nanosystems for antifungal strategies

W Du, Y Gao, L Liu, S Sai, C Ding - International Journal of Molecular …, 2021 - mdpi.com
Fungal infections have become a major health concern, given that invasive infections by
Candida, Cryptococcus, and Aspergillus species have led to millions of mortalities …

Nebulised surface-active hybrid nanoparticles of voriconazole for pulmonary Aspergillosis demonstrate clathrin-mediated cellular uptake, improved antifungal efficacy …

R Kaur, SR Dennison, AJ Burrow… - Journal of …, 2021 - Springer
Background Incidence of pulmonary aspergillosis is rising worldwide, owing to an increased
population of immunocompromised patients. Notable potential of the pulmonary route has …

Nanosystems against candidiasis: a review of studies performed over the last two decades

VHS Araujo, JL Duarte, GC Carvalho… - Critical Reviews in …, 2020 - Taylor & Francis
The crescent number of cases of candidiasis and the increase in the number of infections
developed by non-albicans species and by multi-resistant strains has taken the attention of …

Nanotechnology-based approaches for voriconazole delivery applied to invasive fungal infections

L de Almeida Campos, MT Fin, KS Santos… - Pharmaceutics, 2023 - mdpi.com
Invasive fungal infections increase mortality and morbidity rates worldwide. The treatment of
these infections is still limited due to the low bioavailability and toxicity, requiring therapeutic …

[HTML][HTML] Using the refined Developability Classification System (rDCS) to guide the design of oral formulations

K Beran, E Hermans, R Holm, K Sepassi… - Journal of …, 2024 - Elsevier
Abstract The refined Developability Classification System (rDCS) provides a comprehensive
animal-free approach for assessing biopharmaceutical risks associated with developing oral …

Design, formulation, in-vitro and in-vivo pharmacokinetic evaluation of Nicardipine-nanostructured lipid carrier for transdermal drug delivery system

PR Avula, AK Chettupalli, V Chauhan… - Materials today …, 2023 - Elsevier
Nicardipine hydrochloride (NCP), a calcium channel blocker, may be useful for treating
chronic stable angina and hypertension through a therapeutic transdermal system because …