Exosomes are small (∼ 100 nm) membrane-bound extracellular vesicles released by
various types of cells into biological fluids. They contain proteins, mRNAs and miRNAs as …

Due to an increase in the obesity-associated metabolic syndrome of epidemic proportions,
nonalcoholic fatty liver disease (NAFLD) is becoming a leading cause of hepatocellular …

Emerging evidences have highlighted the crucial role of microRNAs (miRNAs) in the liver
cirrhosis, but the relationship between miR-130a-3p and liver cirrhosis is not entirely clear …

Various cancer stem cell (CSC) biomarkers have been identified for hepatocellular
carcinoma (HCC), but little is known about the implications of heterogeneity and shared …

The incidence and mortality of hepatitis B virus (HBV)-associated hepatocellular carcinoma
(HBV-HCC) is an intractable public health problem in developing countries that is …

Metastasis is a core hallmark of cancer that leads to high mortality of cancer patients,
especially in hepatocellular carcinoma (HCC). However, the underlying mechanisms of long …

Background The active metabolite of 5-Fluorouracil (5FU), used in the treatment of several
types of cancer, acts by inhibiting the thymidylate synthase encoded by the TYMS gene …

AIM To evaluate the levels of miR-192-5p in non-alcoholic fatty liver disease (NAFLD)
models and demonstrate the role of miR-192-5p in lipid accumulation. METHODS Thirty …

For many years, we have faced the complications of viral hepatitis and alcohol-related liver
diseases such as cirrhosis, decompensation, portal hypertension, and hepatocellular …

Hepatocellular carcinoma (HCC) is a tumor with poor prognosis and frequently aggressive.
The development of HCC is associated with fibrosis and cirrhosis, which mainly results from …