Brain-machine interfaces (BMIs) combine methods, approaches, and concepts derived from
neurophysiology, computer science, and engineering in an effort to establish real-time …

The state of the brain and body constantly varies on rapid and slow timescales. These
variations contribute to the apparent noisiness of sensory responses at both the neural and …

Tactile sensory information from facial whiskers provides nocturnal tunnel-dwelling rodents,
including mice and rats, with important spatial and textural information about their immediate …

This book provides eloquent support for the idea that spontaneous neuron activity, far from
being mere noise, is actually the source of our cognitive abilities. In a sequence of" cycles," …

Out of all the human senses, touch is the one that is most often unappreciated, and
undervalued. Yet, the surface of the human body, the skin, is actually one huge sheet of …

Comprehensive measurement of neural activity remains challenging due to the large
numbers of neurons in each brain area. We used volumetric two-photon imaging in mice …

Since the original demonstration that electrical activity generated by ensembles of cortical
neurons can be employed directly to control a robotic manipulator, research on brain …

Theories have proposed that, in sensory cortices, learning can enhance top-down
modulation by higher brain areas while reducing bottom-up sensory drives. To address …

Classical studies have related the spiking of selected neocortical neurons to behavior, but
little is known about activity sampled from the entire neural population. We recorded from …

The tactile somatosensory pathway from whisker to cortex in rodents provides a well-defined
system for exploring the link between molecular mechanisms, synaptic circuits, and …