Mass spectrometry plays a key role in relative quantitative comparisons of proteins in order
to understand their functional role in biological systems upon perturbation. In this review, we …

Over the past decade, chemical labeling with isobaric tandem mass tags, such as isobaric
tags for relative and absolute quantification reagents (iTRAQ) and tandem mass tag (TMT) …

Mass spectrometry-based proteomics is a sophisticated identification tool specializing in
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …

Aims We investigated the association between quantified metabolite, lipid and lipoprotein
measures and incident heart failure hospitalisation (HFH) in the elderly, and examined …

Chronic heart failure (CHF), as a progressive clinical syndrome, is characterized by failure of
enough blood supply from the heart to meet the body's metabolic demands, and there is …

Congenital heart disease (CHD) encompasses all malformations of the heart that occur in
utero and exist at birth and is estimated to affect at least 8.1 per 1000 live births. 1 The …

Background The heart has close interactions with other organs' functions and concomitant
systemic factors such as oxidative stress, nitric oxide (NO), inflammation, and nutrition in …

Background Heart failure (HF) is associated with ventricular dyssynchrony and energetic
inefficiency, which can be alleviated by cardiac resynchronization therapy (CRT). The aim of …

Micro‐RNA s regulate gene expression by directly binding to the target mRNA s. The goal of
the study was to examine the expression profiling of mi RNA s in human failing hearts and …

Dilated cardiomyopathy (DCM) is caused by reduced left ventricular (LV) myocardial
function, which is one of the most common causes of heart failure (HF). We performed …