Altered synthesis of genes associated with short-chain fatty acids in the gut of patients with atrial fibrillation

J Zhang, K Zuo, C Fang, X Yin, X Liu, J Zhong, K Li, J Li… - BMC genomics, 2021 - Springer
Background The gut microbiota provides health benefits in humans by producing short-
chain fatty acids (SCFAs), whose deficiency causes multiple disorders and inflammatory …

[HTML][HTML] Jian-pi-yin decoction attenuates lactose-induced chronic diarrhea in rats by regulating GLP-1 and reducing NHE3 ubiquitination and phosphorylation

J Ma, T Chen, H Xue, M Zhang, Z Li, X Li, Y Wang… - Heliyon, 2023 - cell.com
Abstract Objectives Jian-Pi-Yin decoction (JPY), a prescription derived from the traditional
Chinese medicine Shen-Ling-Bai-Zhu-San, has shown good clinical efficacy in the treatment …

Pharmaceutical research and development: A key informant assessment of whether an" open-science" model could improve clinical research in terms of quality and …

TDN King - 2013 - search.proquest.com
The average cost to develop each new pharmaceutical drug is approximately $1 billion or
more and takes 12-15 years from laboratory concept to an approved drug on the shelf at the …

Delivery Systems for Therapeutic Microbes

K Qiu - 2021 - search.proquest.com
Therapeutic microbes are an emerging pharmaceutical modality in treating diseases
including infections, inflammatory diseases, metabolic disorders, and cancer. While recent …