Host immune responses to Porphyromonas gingivalis antigens.

RD Pathirana, NM O'Brien-Simpson… - Periodontology …, 2010 - search.ebscohost.com
The article discusses the major antigens of porphyromonas gingivalis, a gram-negative
bacteria which is found in the oral cavity. It is stated that the antigens induce an overall …

Strategies for the inhibition of gingipains for the potential treatment of periodontitis and associated systemic diseases

I Olsen, J Potempa - Journal of oral microbiology, 2014 - Taylor & Francis
Gingipains are the major virulence factors of Porphyromonas gingivalis, the main
periodontopathogen. It is expected that inhibition of gingipain activity in vivo could prevent or …

Association of periodontal disease with systemic health indices in dogs and the systemic response to treatment of periodontal disease

JE Rawlinson, RE Goldstein, AM Reiter… - Journal of the …, 2011 - Am Vet Med Assoc
Objective—To determine whether severity of periodontal disease (PD) was associated with
systemic health indices in dogs and whether treatment of PD altered systemic health indices …

Vaccination targeting surface FomA of Fusobacterium nucleatum against bacterial co-aggregation: implication for treatment of periodontal infection and halitosis

PF Liu, W Shi, W Zhu, JW Smith, SL Hsieh, RL Gallo… - Vaccine, 2010 - Elsevier
The mechanical therapy with multiple doses of antibiotics is one of modalities for treatment
of periodontal diseases. However, treatments using multiple doses of antibiotics carry risks …

Advances and challenges in the development of periodontitis vaccines: A comprehensive review

L Liao, Q Wang, Y Feng, G Li, R Lai, F Jameela… - International …, 2024 - Elsevier
Periodontitis is a prevalent polymicrobial disease. It damages soft tissues and alveolar bone,
and causes a significant public-health burden. Development of an advanced therapeutic …

A novel vaccine targeting Fusobacterium nucleatum against abscesses and halitosis

PF Liu, SK Haake, RL Gallo, CM Huang - Vaccine, 2009 - Elsevier
An abscess in a gum pocket, resulting from bacterial infection, is a common source of
chronic halitosis. Although antibiotics are generally prescribed for abscesses, they require …

[HTML][HTML] Toll gates to periodontal host modulation and vaccine therapy

G Hajishengallis - Periodontology 2000, 2009 - ncbi.nlm.nih.gov
Toll-like receptors (TLRs) are central mediators of innate antimicrobial and inflammatory
responses and play instructive roles in the development of the adaptive immune response …

Effects of peri‐implant infection on serum biochemical analysis

L Chaushu, H Tal, A Sculean… - Journal of …, 2021 - Wiley Online Library
Background Peri‐implant disease (PID) has not been directly linked to pathological organ
changes. The present study assessed the dynamics of serum biochemical parameters in a …

Halitosis vaccines targeting FomA, a biofilm-bridging protein of fusobacteria nucleatum

PF Liu, IF Huang, CW Shu… - Current molecular …, 2013 - ingentaconnect.com
Halitosis (bad breath) is estimated to influence more than half of the world's population with
varying degree of intensity. More than 85% of halitosis originates from oral bacterial …

Identification of gingipain‐specific I‐Ab‐restricted CD4+ T cells following mucosal colonization with Porphyromonas gingivalis in C57BL/6 mice

PD Bittner‐Eddy, LA Fischer… - Molecular oral …, 2013 - Wiley Online Library
Chronic periodontitis is associated with P orphyromonas gingivalis infection. Although
virulence factors of P. gingivalis are hypothesized to contribute to the pathogenesis of …