It is only recently that a number of studies on synaptic plasticity in the hippocampus and
other brain areas have considered that a heterosynaptic modulatory input could be recruited …

Because of our limited knowledge of the functional role of the thalamostriatal system, this
massive network is often ignored in models of the pathophysiology of brain disorders of …

A wealth of research focuses on the decision-making processes that animals and humans
employ when selecting actions in the face of reward and punishment. Initially such work …

The human striatum is functionally organized into limbic, associative, and sensorimotor
subdivisions, which process information related to emotional, cognitive, and motor function …

The effect of immediate versus delayed feedback on rule-based and information-integration
category learning was investigated. Accuracy rates were examined to isolate global …

Neurotransmitters and neuromodulators, such as dopamine, participate in a wide range of
behavioral and cognitive functions in the adult brain, including movement, cognition, and …

A fundamental question is whether people have available one category learning system, or
many. Most multiple systems advocates postulate one explicit and one implicit system …

For normal regulation of motor, affective, and cognitive functions, dopamine provides an
essential modulation of glutamate transmission within multiple brain regions. This paper will …

Dysfunction of neostriatal medium spiny neurons (MSNs) is hypothesized to underlie late-
stage motor complications of Parkinson disease (PD). The authors demonstrate shortened …

Cortical glutamatergic and nigral dopaminergic afferents impinge on projection spiny
neurons of the striatum, providing the most significant inputs to this structure. Isolated …