Design and synthesis of novel antimicrobial agents

Z Breijyeh, R Karaman - Antibiotics, 2023 - mdpi.com
The necessity for the discovery of innovative antimicrobials to treat life-threatening diseases
has increased as multidrug-resistant bacteria has spread. Due to antibiotics' availability over …

Quality by design approach in liposomal formulations: Robust product development

W Alshaer, H Nsairat, Z Lafi, OM Hourani, A Al-Kadash… - Molecules, 2022 - mdpi.com
Nanomedicine is an emerging field with continuous growth and differentiation. Liposomal
formulations are a major platform in nanomedicine, with more than fifteen FDA-approved …

[HTML][HTML] Liposome-loaded polymeric microneedles for enhanced skin deposition of rifampicin

QK Anjani, AK Pandya, S Demartis… - International Journal of …, 2023 - Elsevier
Methicillin-resistant Staphylococcus aureus (MRSA) is a prevailing bacterial pathogen
linked to superficial skin and soft tissue infections (SSTIs). Rifampicin (RIF), a potent …

Emerging strategies in nanotechnology to treat respiratory tract infections: realizing current trends for future clinical perspectives

M Chen, Z Shou, X Jin, Y Chen - Drug Delivery, 2022 - Taylor & Francis
A boom in respiratory tract infection cases has inflicted a socio-economic burden on the
healthcare system worldwide, especially in developing countries. Limited alternative …

Liposomes-based drug delivery systems of anti-biofilm agents to combat bacterial biofilm formation

Z Makhlouf, AA Ali, MH Al-Sayah - Antibiotics, 2023 - mdpi.com
All currently approved antibiotics are being met by some degree of resistance by the
bacteria they target. Biofilm formation is one of the crucial enablers of bacterial resistance …

Antibiotic loaded inhalable liposomal nanoparticles against lower respiratory tract infections: Challenges, recent advances, and future perspectives

VK Panthi, KE Fairfull-Smith, N Islam - Journal of Drug Delivery Science …, 2024 - Elsevier
Lower respiratory tract infections (LRTIs) are inherited disorders which often causes chronic
respiratory infections for which patients repeatedly receive oral antibiotics, particularly …

[HTML][HTML] Advanced pulmonary drug delivery formulations for the treatment of cystic fibrosis

A Parihar, BG Prajapati, H Paliwal, M Shukla… - Drug Discovery …, 2023 - Elsevier
Cystic fibrosis (CF), a fatal genetic condition, causes thick, sticky mucus. It also causes
pancreatic dysfunction, bacterial infection, and increased salt loss. Currently available …

Overcoming barriers in cystic fibrosis therapy through inhalational lipid nanoparticles: Challenges and advances

MM Anjum, KK Patel, S Bhattacharya, DK Arya… - Journal of Drug Delivery …, 2023 - Elsevier
Cystic fibrosis (CF) is a genetic disorder that follows an autosomal recessive pattern of
inheritance and is characterized by mutations in the cystic fibrosis transmembrane …

[PDF][PDF] Optimization and formulation of doxorubicin (DOX) loaded liposome well-used in chemotherapy involving quality by design (QbD): a transitory research

R Pal, P Pandey, VK Maurya, A Saxena… - European Chemical …, 2023 - researchgate.net
Nanomedicine is a developing discipline that is constantly evolving and differentiating.
Liposomal preparation has an important role in nanomedicine as a novel platform. QbD …

Tryptone-stabilized silver nanoparticles' potential to mitigate planktonic and biofilm growth forms of Serratia marcescens

P Pandey, K Meher, B Falcao, M Lopus… - JBIC Journal of Biological …, 2023 - Springer
Several microbial pathogens are capable of forming biofilms. These microbial communities
pose a serious challenge to the healthcare sector as they are quite difficult to combat. Given …