The incidence and mortality rate of cancer has been quickly increasing in the past decades.
At present, cancer has become the leading cause of death worldwide. Most of the cancers …

Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …

MYH9 has dual functions in tumors. However, its role in inducing tumor stemness in
hepatocellular carcinoma (HCC) is not yet determined. Here, we found that MYH9 is an …

Uncontrolled growth and metastasis of cancer cells is an increasing challenge for
overcoming cancer, and improving survival of patients. Complicated signaling networks …

About 250 million people worldwide are chronically infected with Hepatitis B virus (HBV),
contributing to a large burden on public health. Despite the existence of vaccines and …

Hepatocellular carcinoma (HCC) is one of the lethal and leading types of cancer threatening
the globe with a high mortality rate. STAT3 is an oncogenic transcription factor that is …

Hepatocellular carcinoma (HCC) is considered one of the greatest challenges to human life
and is the most common form of liver cancer. Treatment of HCC depends on chemotherapy …

Background Autophagy plays an important role in regulating cisplatin (CDDP) resistance in
gastric cancer cells. However, the underlying mechanism of methioninase (METase) in the …

STAT3 is a key oncogenic transcription factor, often overactivated in several human cancers
including hepatocellular carcinoma (HCC). STAT3 modulates the expression of genes that …

Hepatocellular carcinoma (HCC) is a prevalent human malignancy with high morbidity
worldwide. Hepatocarcinogenesis is a complex multistep process, and its underlying …