Exosomes are small extracellular vesicles 40–160 nm in diameter that are secreted by
almost all cell types. Exosomes can carry diverse cargo including RNA, DNA, lipids …

Diabetes-associated complications, such as retinopathy, nephropathy, cardiomyopathy, and
atherosclerosis, the main consequences of long-term hyperglycemia, often lead to organ …

Cardiovascular diseases (CVDs) are one of the leading causes of morbidity and mortality.
Standard therapies have failed to significantly increase patients' survival. Moreover, the …

Several lines of evidence have revealed the potential of microRNAs (miRNAs, miRs) as
biomarkers for detecting diabetic cardiomyopathy, although their functions in hyperglycemic …

Type 2 diabetes mellitus (T2DM) is one of the most prevalent metabolic disorders worldwide.
However, T2DM still remains underdiagnosed and undertreated resulting in poor quality of …

Diabetic Cardiomyopathy (DCM) is characterized by myocardial dysfunction caused by
diabetes mellitus. After-effects of diabetic cardiomyopathy are far more lethal than non …

Extracellular vesicles (EVs) are small anuclear vesicles, delimited by a lipid bilayer,
released by almost all cell types, carrying functionally active biological molecules that can …

Diabetic cardiomyopathy (DCM) represents one of the typical complications associated with
diabetes. It has been described as anomalies in heart function and structure, with …

OBJECTIVE: The aim of this study was to observe the protective effects of SGLT-2 inhibitors
on diabetic cardiomyopathy. MATERIALS AND METHODS: After constructing a diabetic rat …

MicroRNA 34a (miR-34a) is elevated in the heart in a setting of cardiac stress or pathology,
and we previously reported that inhibition of miR-34a in vivo provided protection in a setting …