Organ-on-a-chip: Recent breakthroughs and future prospects

Q Wu, J Liu, X Wang, L Feng, J Wu, X Zhu… - Biomedical engineering …, 2020 - Springer
The organ-on-a-chip (OOAC) is in the list of top 10 emerging technologies and refers to a
physiological organ biomimetic system built on a microfluidic chip. Through a combination of …

Understanding cell‐cell communication and signaling in the colorectal cancer microenvironment

S AlMusawi, M Ahmed, AS Nateri - Clinical and translational …, 2021 - Wiley Online Library
Carcinomas are complex heterocellular systems containing epithelial cancer cells, stromal
fibroblasts, and multiple immune cell‐types. Cell‐cell communication between these tumor …

3D bioprinting of tumor models for cancer research

Y Kang, P Datta, S Shanmughapriya… - ACS Applied Bio …, 2020 - ACS Publications
The exact mechanistic understanding of cancer metastasis continues to be unknown,
although it is a major cause of death worldwide. Along with the tumor mass, the tumor …

Membrane trafficking in health and disease

R Yarwood, J Hellicar… - Disease models & …, 2020 - journals.biologists.com
Membrane trafficking pathways are essential for the viability and growth of cells, and play a
major role in the interaction of cells with their environment. In this At a Glance article and …

Modeling cell communication in cancer with organoids: making the complex simple

E Fiorini, L Veghini, V Corbo - Frontiers in cell and developmental …, 2020 - frontiersin.org
Homotypic and heterotypic interactions between cells are of crucial importance in
multicellular organisms for the maintenance of physiological functions. Accordingly, changes …

[HTML][HTML] Advanced usage of Ti3C2Tx MXenes for photothermal therapy on different 3D breast cancer models

G Perini, A Rosenkranz, G Friggeri, D Zambrano… - Biomedicine & …, 2022 - Elsevier
Globally, breast cancer is the most diagnosed invasive cancer among women. Current
therapies (eg, chemotherapy) show numerous limitations due to the lack of selectivity and …

Engineering tissue barrier models on hydrogel microfluidic platforms

D Vera, M Garcia-Diaz, N Torras… - … applied materials & …, 2021 - ACS Publications
Tissue barriers play a crucial role in human physiology by establishing tissue
compartmentalization and regulating organ homeostasis. At the interface between the …

A focused review on three-dimensional bioprinting technology for artificial organ fabrication

S Panda, S Hajra, K Mistewicz, B Nowacki… - Biomaterials …, 2022 - pubs.rsc.org
Three-dimensional (3D) bioprinting technology has attracted a great deal of interest
because it can be easily adapted to many industries and research sectors, such as …

Induction of four‐dimensional spatiotemporal geometric transformations in high cell density tissues via shape‐changing hydrogels

YB Lee, O Jeon, SJ Lee, A Ding… - Advanced functional …, 2021 - Wiley Online Library
Developing and healing tissues begin as cellular condensations. Spatiotemporal changes in
tissue geometry, transformations in the spatial distribution of the cells, and extracellular …

Immunotherapy of glioblastoma: current strategies and challenges in tumor model development

B Majc, M Novak, N Kopitar-Jerala, A Jewett, B Breznik - Cells, 2021 - mdpi.com
Glioblastoma is the most common brain malignant tumor in the adult population, and
immunotherapy is playing an increasingly central role in the treatment of many cancers …