Metabolites of glycolytic metabolism have been identified as signaling molecules and
regulators of gene expression, in addition to their basic function as major energy and …

Metabolism, including glycolysis, oxidative phosphorylation, fatty acid oxidation, and other
metabolic pathways, impacts the phenotypes and functions of immune cells. The metabolic …

Nutrition has broad impacts on all physiological processes. However, how nutrition affects
human immunity remains largely unknown. Here we explored the impact of a dietary …

T-cell-mediated immune responses aim to protect mammals against cancers and infections,
and are also involved in the pathogenesis of various inflammatory or autoimmune diseases …

Inflammatory bowel diseases (IBDs), including ulcerative colitis and Crohn's disease, are
characterized by chronic idiopathic inflammation of gastrointestinal tract. Although the …

Abstract Ethnopharmacological relevance Jingfang Granule (JFG) is a Traditional Chinese
Medicine prescription to empirically treat skin disease such as urticaria in clinical practice …

The effect of the serine/glycine-free diet (− SG diet) on colorectal cancer (CRC) remains
unclear; meanwhile, programmed death-1 (PD-1) inhibitors are less effective for most CRC …

Inducible regulatory T (iTreg) cells play a central role in immune suppression. As iTreg cells
are differentiated from activated T (Th0) cells, cell metabolism undergoes dramatic changes …

The metabolic pathways of central carbon metabolism, glycolysis and oxidative
phosphorylation (OXPHOS), are important host factors that determine the outcome of viral …

Regulatory T (T reg) cells are required for the maintenance of immune homeostasis. Both
TGF-β signaling and epigenetic modifications are important for Foxp3 induction, but how …