[HTML][HTML] T cells in health and disease

L Sun, Y Su, A Jiao, X Wang, B Zhang - Signal transduction and …, 2023 - nature.com
T cells are crucial for immune functions to maintain health and prevent disease. T cell
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …

[HTML][HTML] T helper cells: the modulators of inflammation in multiple sclerosis

M Kunkl, S Frascolla, C Amormino, E Volpe, L Tuosto - Cells, 2020 - mdpi.com
Multiple sclerosis (MS) is a chronic neurodegenerative disease characterized by the
progressive loss of axonal myelin in several areas of the central nervous system (CNS) that …

Th9 cells: differentiation and disease

MH Kaplan - Immunological reviews, 2013 - Wiley Online Library
CD 4+ T‐helper cells regulate immunity and inflammation through the acquisition of
potential to secrete specific cytokines. The acquisition of cytokine‐secreting potential, in a …

A brief history of IL-9

R Goswami, MH Kaplan - The Journal of Immunology, 2011 - journals.aai.org
IL-9 was first described in the late 1980s as a member of a growing number of cytokines that
had pleiotropic functions in the immune system. Although many biological functions have …

Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination

A Rostami, B Ciric - Journal of the neurological sciences, 2013 - Elsevier
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). The
etiology of MS is not well understood, but it is believed that myelin-specific CD4+ T cells play …

[HTML][HTML] Cellular sources and immune functions of interleukin-9

RJ Noelle, EC Nowak - Nature Reviews Immunology, 2010 - nature.com
Abstract Interleukin-9 (IL-9) has attracted renewed interest owing to the identification of its
expression by multiple T helper (TH) cell subsets, including TH2 cells, TH9 cells, TH17 cells …

[HTML][HTML] Involvement of IL-9 in Th17-associated inflammation and angiogenesis of psoriasis

TP Singh, MP Schön, K Wallbrecht… - PloS one, 2013 - journals.plos.org
It is thought that a Th1/Th17-weighted immune response plays a predominant role in the
pathogenesis of psoriasis. Our findings now indicate a link between IL-9, a Th2 and Th9 …

Human TH9 Cells Are Skin-Tropic and Have Autocrine and Paracrine Proinflammatory Capacity

C Schlapbach, A Gehad, C Yang… - Science translational …, 2014 - science.org
T helper type 9 (TH9) cells can mediate tumor immunity and participate in autoimmune and
allergic inflammation in mice, but little is known about the TH9 cells that develop in vivo in …

[HTML][HTML] Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells

W Elyaman, R Bassil, EM Bradshaw, W Orent… - Immunity, 2012 - cell.com
Summary Interleukin 9 (IL-9) is a pleiotropic cytokine that can regulate autoimmune
responses by enhancing regulatory CD4+ FoxP3+ T regulatory (Treg) cell survival and T …

[HTML][HTML] Characteristics of hematopoietic stem cells of umbilical cord blood

A Hordyjewska, Ł Popiołek, A Horecka - Cytotechnology, 2015 - Springer
Umbilical cord blood collected from the postpartum placenta and cord is a rich source of
hematopoietic stem cells (HSCs) and is an alternative to bone marrow transplantation. In this …