RNAi crop protection advances

A Hernández-Soto, R Chacón-Cerdas - International Journal of Molecular …, 2021 - mdpi.com
RNAi technology is a versatile, effective, safe, and eco-friendly alternative for crop
protection. There is plenty of evidence of its use through host-induced gene silencing (HIGS) …

[HTML][HTML] Vascular endothelial growth factor (VEGF) delivery approaches in regenerative medicine

N Beheshtizadeh, M Gharibshahian, M Bayati… - Biomedicine & …, 2023 - Elsevier
The utilization of growth factors in the process of tissue regeneration has garnered
significant interest and has been the subject of extensive research. However, despite the …

Designing electrospun fiber platforms for efficient delivery of genetic material and genome editing tools

DL Puhl, D Mohanraj, DW Nelson, RJ Gilbert - Advanced drug delivery …, 2022 - Elsevier
Electrospun fibers are versatile biomaterial platforms with great potential to support
regeneration. Electrospun fiber characteristics such as fiber diameter, degree of alignment …

Gene therapy: A promising approach for breast cancer treatment

NT Dastjerd, A Valibeik… - Cell biochemistry …, 2022 - Wiley Online Library
Breast cancer (BC) is the most prevalent malignancy and the second leading cause of death
among women worldwide that is caused by numerous genetic and environmental factors …

[HTML][HTML] Targeted nanocarrier-based drug delivery strategies for improving the therapeutic efficacy of PARP inhibitors against ovarian cancer

P Gralewska, A Gajek, A Marczak… - International Journal of …, 2024 - mdpi.com
The current focus of ovarian cancer (OC) research is the improvement of treatment options
through maximising drug effectiveness. OC remains the fifth leading cause of cancer …

Recent advances in polymeric and lipid stimuli-responsive nanocarriers for cell-based cancer immunotherapy

A Gharatape, B Amanzadi, F Mohamadi… - …, 2024 - Taylor & Francis
Conventional cancer therapy has major limitations, including non-specificity, unavoidable
side effects, low specific tumor accumulation and systemic toxicity. In recent years, more …

Polyplex-loaded hydrogels for local gene delivery to human dermal fibroblasts

JA Duran-Mota, JQ Yani, BD Almquist… - ACS Biomaterials …, 2021 - ACS Publications
Impaired cutaneous healing leading to chronic wounds affects between 2 and 6% of the total
population in most developed countries and it places a substantial burden on healthcare …

3D printed gene-activated sodium alginate hydrogel scaffolds

MA Khvorostina, AV Mironov, IA Nedorubova… - Gels, 2022 - mdpi.com
Gene therapy is one of the most promising approaches in regenerative medicine to restore
damaged tissues of various types. However, the ability to control the dose of bioactive …

Dendrimers as non-viral vectors in gene-directed enzyme prodrug therapy

AA Chis, CM Dobrea, LL Rus, A Frum, C Morgovan… - Molecules, 2021 - mdpi.com
Gene-directed enzyme prodrug therapy (GDEPT) has been intensively studied as a
promising new strategy of prodrug delivery, with its main advantages being represented by …

Environmental and human risk assessment of polymer nanocarriers: a review on current analytical challenges and promising approaches

DMM Das, J Travas-Sejdic, E Leitao… - Environmental Science …, 2025 - pubs.rsc.org
Polymer nanocarriers (PNCs) are designed to deliver active ingredients in pharmaceuticals,
food science and agricultural applications and it is essential to ensure their safety towards …