Obesity and the risk of cardiometabolic diseases

PL Valenzuela, P Carrera-Bastos… - Nature reviews …, 2023 - nature.com
The prevalence of obesity has reached pandemic proportions, and now approximately 25%
of adults in Westernized countries have obesity. Recognized as a major health concern …

The related metabolic diseases and treatments of obesity

M Yang, S Liu, C Zhang - Healthcare, 2022 - mdpi.com
Obesity is a chronic disease characterized by the abnormal or excessive accumulation of
body fat, affecting more than 1 billion people worldwide. Obesity is commonly associated …

Enhancing intestinal barrier efficiency: A novel metabolic diseases therapy

Y Zhang, X Zhu, X Yu, P Novák, Q Gui, K Yin - Frontiers in Nutrition, 2023 - frontiersin.org
Physiologically, the intestinal barrier plays a crucial role in homeostasis and nutrient
absorption and prevents pathogenic entry, harmful metabolites, and endotoxin absorption …

Adipokines and their potential impacts on susceptibility to myocardial ischemia/reperfusion injury in diabetes

R Han, H Huang, J Zhu, X Jin, Y Wang, Y Xu… - Lipids in Health and …, 2024 - Springer
Coronary artery disease has a high mortality rate and is a striking public health concern,
affecting a substantial portion of the global population. On the early onset of myocardial …

Body roundness index improves the predictive value of cardiovascular disease risk in hypertensive patients with obstructive sleep apnea: a cohort study

X Cai, S Song, J Hu, Q Zhu, W Yang… - Clinical and …, 2023 - Taylor & Francis
Background Obesity, especially visceral obesity, plays an important role in the progression
of cardiovascular disease (CVD). The body roundness index (BRI) is a new measure of …

Diagnostic and prognostic value of serum omentin-1 in sepsis: A prospective study in critically ill patients

I Karampela, NG Vallianou, D Tsilingiris… - Medicina, 2023 - mdpi.com
Background and Objectives: Omentin-1, also known as intelectin-1, is a novel adipokine with
anti-inflammatory activities implicated in inflammatory diseases and sepsis. We aimed to …

Comparison of computed tomography and dual-energy X-ray absorptiometry in the evaluation of body composition in patients with obesity

F Palmas, A Ciudin, R Guerra, D Eiroa… - Frontiers in …, 2023 - frontiersin.org
Objective a) To evaluate the accuracy of the pre-existing equations (based on cm2 provided
by CT images), to estimate in kilograms (Kg) the body composition (BC) in patients with …

Bidirectional communication between brain and visceral white adipose tissue: its potential impact on Alzheimer's disease

X Huang, YJ Wang, Y Xiang - EBioMedicine, 2022 - thelancet.com
A variety of axes between brain and abdominal organs have been reported, but the
interaction between brain and visceral white adipose tissue (vWAT) remains unclear. In this …

Adipose Tissue‐Derived Extracellular Vesicles: A Promising Biomarker and Therapeutic Strategy for Metabolic Disorders

W Liu, T Liu, Q Zhao, J Ma, J Jiang… - Stem Cells …, 2023 - Wiley Online Library
Adipose tissue plays an important role in systemic energy metabolism, and its dysfunction
can lead to severe metabolic disorders. Various cells in adipose tissue communicate with …

Depot-specific adipose tissue modulation by SGLT2 inhibitors and GLP1 agonists mediates their cardioprotective effects in metabolic disease

NMZ Bakkar, I AlZaim, AF El-Yazbi - Clinical Science, 2022 - portlandpress.com
Abstract Sodium-glucose transporter-2 inhibitors (SGLT-2i) and glucagon-like peptide 1
(GLP-1) receptor agonists are newer antidiabetic drug classes, which were recently shown …