Is the routine use of local antibiotics in the management of periprosthetic joint infections justified?

J Bourget-Murray, M Azad, W Gofton… - Hip …, 2023 - journals.sagepub.com
Periprosthetic joint infection (PJI) following total hip and total knee arthroplasty continues to
be a leading cause of re-operation and revision arthroplasty. Not only is the treatment of PJI …

Effects of different doses of vancomycin powder in total knee and hip arthroplasty on the periprosthetic joint infection rate: a systematic review and meta-analysis

S Liao, Z Yang, X Li, J Chen, J Liu - Journal of Orthopaedic Surgery and …, 2022 - Springer
Background Periprosthetic joint infection (PJI) following total joint arthroplasty (TJA) is a
serious complication for patients. Some joint surgeons have tried to use vancomycin powder …

Vancomycin powder in total joint replacement: what is the evidence, and is it good enough to support its routine use?

F Mancino, V Gant, DRM Meek… - The Bone & Joint …, 2023 - boneandjoint.org.uk
Periprosthetic joint infection (PJI) is a devastating complication of total hip (THA) and total
knee arthroplasty (TKA) with an incidence ranging from 1% to 2% after primary procedures …

Dosage, efficacy, and safety of intra-articular vancomycin for prophylaxis of periprosthetic joint infection caused by methicillin-resistant staphylococcus aureus after …

J Wei, K Tong, H Wang, Y Wen… - Antimicrobial Agents and …, 2022 - Am Soc Microbiol
Although intra-articular vancomycin powder (VP) is sometimes applied before the closure of
the incision to prevent periprosthetic joint infection (PJI) after joint replacement, the dosage …

[HTML][HTML] Intraarticular vancomycin decreased the risk of acute postoperative periprosthetic joint infection without increasing complication in primary total joint …

M Hu, Y Zhang, X Yang, Y Wang, H Xu… - International Journal of …, 2023 - Elsevier
Objectives To investigate the preventive effect of intraarticularly administered vancomycin on
acute postoperative periprosthetic joint infection (PJI) in total joint arthroplasty (TJA) …

Preclosure povidone‐iodine lavage in total hip replacement surgery: Infection outcomes and cost–benefit analysis

SK Israel, E Jaramillo, WD Liska - Veterinary Surgery, 2023 - Wiley Online Library
Objective To report the outcomes and cost–benefit analysis of preclosure povidone‐iodine
lavage (PrePIL) used to reduce the risk of infection following total hip replacement (THR) …

[HTML][HTML] The effects of chlorhexidine, povidone-iodine and vancomycin on growth and biofilms of pathogens that cause prosthetic joint infections: an in-vitro model

VE Coles, L Puri, M Bhandari, TJ Wood… - Journal of Hospital …, 2024 - Elsevier
Background Chlorhexidine gluconate (CHG) and povidone-iodine (PI) are commonly used
to prevent prosthetic joint infection (PJI) during total joint replacement; however, their …

Does the use of topical vancomycin during primary hip or knee arthroplasty protect from infections?

F Laudet, A Gay, H Dutronc, T Fabre, P Meynard… - … & Traumatology: Surgery …, 2024 - Elsevier
Background Infection is one of the main complications of hip and knee arthroplasties.
Topical application vancomycin to prevent postoperative infections is efficient in spine …

[HTML][HTML] Increased rate of early periprosthetic joint infection in total hip arthroplasty with the use of alternatives to cefazolin despite additional gram-negative coverage

D Ortiz III, GM Teo, K Lygrisse, VK Aggarwal, WJ Long - Arthroplasty today, 2022 - Elsevier
Background Periprosthetic joint infection (PJI) remains one of the most devastating
complications following total joint arthroplasty. Appropriate prophylactic antimicrobial …

[HTML][HTML] Topical Application of Vancomycin Powder to Prevent Infections after Massive Bone Resection and the implantation of Megaprostheses in Orthopaedic …

L Andreani, E Ipponi, G Varchetta… - Malaysian …, 2024 - ncbi.nlm.nih.gov
Materials and methods Fifty oncological cases treated with massive bone resection and the
implant of a megaprosthesis were included in our study. Among them, 22 [(GGroup A) …