Physical models of collective cell migration
Collective cell migration is a key driver of embryonic development, wound healing, and
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …
some types of cancer invasion. Here, we provide a physical perspective of the mechanisms …
[HTML][HTML] Substrate curvature as a cue to guide spatiotemporal cell and tissue organization
SJP Callens, RJC Uyttendaele, LE Fratila-Apachitei… - Biomaterials, 2020 - Elsevier
Recent evidence clearly shows that cells respond to various physical cues in their
environments, guiding many cellular processes and tissue morphogenesis, pathology, and …
environments, guiding many cellular processes and tissue morphogenesis, pathology, and …
Programming multicellular assembly with synthetic cell adhesion molecules
Cell adhesion molecules are ubiquitous in multicellular organisms, specifying precise cell–
cell interactions in processes as diverse as tissue development, immune cell trafficking and …
cell interactions in processes as diverse as tissue development, immune cell trafficking and …
The actin cortex at a glance
P Chugh, EK Paluch - Journal of cell science, 2018 - journals.biologists.com
Precisely controlled cell deformations are key to cell migration, division and tissue
morphogenesis, and have been implicated in cell differentiation during development, as well …
morphogenesis, and have been implicated in cell differentiation during development, as well …
Motility-driven glass and jamming transitions in biological tissues
Cell motion inside dense tissues governs many biological processes, including embryonic
development and cancer metastasis, and recent experiments suggest that these tissues …
development and cancer metastasis, and recent experiments suggest that these tissues …
Tensile forces and mechanotransduction at cell–cell junctions
G Charras - Current Biology, 2018 - cell.com
Cell–cell junctions are specializations of the plasma membrane responsible for physically
integrating cells into tissues. We are now beginning to appreciate the diverse impacts that …
integrating cells into tissues. We are now beginning to appreciate the diverse impacts that …
A density-independent rigidity transition in biological tissues
Cell migration is important in many biological processes, including embryonic development,
cancer metastasis and wound healing. In these tissues, a cell's motion is often strongly …
cancer metastasis and wound healing. In these tissues, a cell's motion is often strongly …
Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers
Actomyosin machinery endows cells with contractility at a single-cell level. However, within a
monolayer, cells can be contractile or extensile based on the direction of pushing or pulling …
monolayer, cells can be contractile or extensile based on the direction of pushing or pulling …
Adhesion forces and cortical tension couple cell proliferation and differentiation to drive epidermal stratification
To establish and maintain organ structure and function, tissues need to balance stem cell
proliferation and differentiation rates and coordinate cell fate with position. By quantifying …
proliferation and differentiation rates and coordinate cell fate with position. By quantifying …
Adhesion functions in cell sorting by mechanically coupling the cortices of adhering cells
Differential cell adhesion and cortex tension are thought to drive cell sorting by controlling
cell-cell contact formation. Here, we show that cell adhesion and cortex tension have …
cell-cell contact formation. Here, we show that cell adhesion and cortex tension have …