Epilepsy and brain network hubs

J Royer, BC Bernhardt, S Larivière, E Gleichgerrcht… - …, 2022 - Wiley Online Library
Epilepsy is a disorder of brain networks. A better understanding of structural and dynamic
network properties may improve epilepsy diagnosis, treatment, and prognostics. Hubs are …

Neurobehavioural comorbidities of epilepsy: towards a network-based precision taxonomy

BP Hermann, AF Struck, RM Busch, A Reyes… - Nature Reviews …, 2021 - nature.com
Cognitive and behavioural comorbidities are prevalent in childhood and adult epilepsies
and impose a substantial human and economic burden. Over the past century, the classic …

Temporal lobe epilepsy and psychiatric comorbidity

V Vinti, GB Dell'Isola, G Tascini, E Mencaroni… - Frontiers in …, 2021 - frontiersin.org
Most focal seizures originate in the temporal lobe and are commonly divided into mesial and
lateral temporal epilepsy, depending upon the neuronal circuitry involved. The hallmark …

Uncovering the biological basis of control energy: Structural and metabolic correlates of energy inefficiency in temporal lobe epilepsy

X He, L Caciagli, L Parkes, J Stiso, TM Karrer… - Science …, 2022 - science.org
Network control theory is increasingly used to profile the brain's energy landscape via
simulations of neural dynamics. This approach estimates the control energy required to …

Development and application of the International Classification of Cognitive Disorders in Epilepsy (IC-CoDE): Initial results from a multi-center study of adults with …

CR McDonald, RM Busch, A Reyes, K Arrotta… - …, 2023 - psycnet.apa.org
Abstract [Correction Notice: An Erratum for this article was reported online in
Neuropsychology on Sep 15 2022 (see record 2023-01997-001). In the original article, there …

Resting state network dynamic reconfiguration and neuropsychological functioning in temporal lobe epilepsy: An HD-EEG investigation

GM Duma, A Danieli, MG Mattar, M Baggio, A Vettorel… - Cortex, 2022 - Elsevier
Temporal lobe epilepsy (TLE) is nowadays considered a network disorder impacting several
cognitive domains. In this work we investigated dynamic network reconfiguration differences …

'Hippocampal innate inflammatory gliosis only'in pharmacoresistant temporal lobe epilepsy

A Grote, DH Heiland, J Taube, C Helmstaedter… - Brain, 2023 - academic.oup.com
Drug-resistant mesial-temporal lobe epilepsy is a devastating disease with seizure onset in
the hippocampal formation. A fraction of hippocampi samples from epilepsy-surgical …

Mechanisms for cognitive impairment in epilepsy: moving beyond seizures

MR Khalife, RC Scott, AE Hernan - Frontiers in neurology, 2022 - frontiersin.org
There has been a major emphasis on defining the role of seizures in the causation of
cognitive impairments like memory deficits in epilepsy. Here we focus on an alternative …

Altered communication dynamics reflect cognitive deficits in temporal lobe epilepsy

M Girardi‐Schappo, F Fadaie, HM Lee, B Caldairou… - …, 2021 - Wiley Online Library
Objective Although temporal lobe epilepsy (TLE) is recognized as a system‐level disorder,
little work has investigated pathoconnectomics from a dynamic perspective. By leveraging …

Cognitive phenotypes in frontal lobe epilepsy

K Arrotta, A Reyes, E Kaestner, CR McDonald… - …, 2022 - Wiley Online Library
Objective Neuropsychological profiles are heterogeneous both across and within epilepsy
syndromes, but especially in frontal lobe epilepsy (FLE), which has complex semiology and …