Extracellular vesicles: powerful candidates in nano-drug delivery systems

X Liu, Y Cao, S Wang, J Liu, H Hao - Drug Delivery and Translational …, 2024 - Springer
Extracellular vesicles (EVs), which are nanoparticles that are actively released by cells,
contain a variety of biologically active substances, serve as significant mediators of …

Biomimetic nanocarriers in cancer therapy: Based on intercellular and cell-tumor microenvironment communication

H Mengyuan, L Aixue, G Yongwei, C Qingqing… - Journal of …, 2024 - Springer
Inspired by the concept of “natural camouflage,” biomimetic drug delivery systems have
emerged to address the limitations of traditional synthetic nanocarriers, such as poor …

Application of engineered extracellular vesicles for targeted tumor therapy

F Zhang, J Guo, Z Zhang, M Duan, G Wang… - Journal of biomedical …, 2022 - Springer
All cells, including prokaryotes and eukaryotes, could release extracellular vesicles (EVs).
EVs contain many cellular components, including RNA, and surface proteins, and are …

Tailoring of apoptotic bodies for diagnostic and therapeutic applications: advances, challenges, and prospects

X Miao, X Wu, W You, K He, C Chen, JL Pathak… - Journal of Translational …, 2024 - Springer
Apoptotic bodies (ABs) are extracellular vesicles released during apoptosis and possess
diverse biological activities. Initially, ABs were regarded as garbage bags with the main …

[HTML][HTML] Leveraging high-throughput screening technologies in targeted mRNA delivery

Y Zhang, Z Gao, X Yang, Q Xu, Y Lu - Materials Today Bio, 2024 - Elsevier
Messenger ribonucleic acid (mRNA) has emerged as a promising molecular preventive and
therapeutic approach that opens new avenues for healthcare. Although the use of delivery …

Runx3 Acts as Homodimeric Chromatin Binding Factor Regulating Heterochromatin-Mediated Cancerous Phenotype

SA Mahmoud, I Bonne, AY Sim, GL Abuelenain - bioRxiv, 2024 - biorxiv.org
The recent paradoxical dual citizenships of Runt-related transcription factor 3 (Runx3) in
tumorigenesis remains poorly characterized. Here, we report the oncogenic capacity of …