Biologically active isoquinoline alkaloids covering 2014–2018
XF Shang, CJ Yang… - Medicinal research …, 2020 - Wiley Online Library
Isoquinoline alkaloids, an important class of N‐based heterocyclic compounds, have
attracted considerable attention from researchers worldwide since the early 19th century …
attracted considerable attention from researchers worldwide since the early 19th century …
Structure-activity-relationship and mechanistic insights for anti-HIV natural products
Acquired Immunodeficiency Syndrome (AIDS), which chiefly originatesfroma retrovirus
named Human Immunodeficiency Virus (HIV), has impacted about 70 million people …
named Human Immunodeficiency Virus (HIV), has impacted about 70 million people …
[HTML][HTML] Chemical diversity and activity profiles of HIV-1 reverse transcriptase inhibitors from plants
KC Chinsembu - Revista Brasileira de Farmacognosia, 2019 - Elsevier
Current challenges to antiretroviral therapy have opened new vistas in the search for novel
drugs from natural products. This review focusses on plants as sources of inhibitors for …
drugs from natural products. This review focusses on plants as sources of inhibitors for …
A comprehensive overview on the role of phytocompounds in human immunodeficiency virus treatment
Acquired immune deficiency syndrome (AIDS) is a worldwide epidemic caused by human
immunodeficiency virus (HIV) infection. Newer medicines for eliminating the viral reservoir …
immunodeficiency virus (HIV) infection. Newer medicines for eliminating the viral reservoir …
In Vitro Cytotoxicity and Anti-HIV Activity of Crude Extracts of Croton macrostachyus, Croton megalocarpus and Croton dichogamus
Introduction Human immunodeficiency virus (HIV) affects the body's defense mechanisms
and leads to a number of opportunistic infections which later cause fatality as a result of an …
and leads to a number of opportunistic infections which later cause fatality as a result of an …
Role of diosgenin extracted from Helicteres isora L in suppression of HIV-1 replication: An in vitro preclinical study
Background Diosgenin, an essential sapogenin steroid with significant biological
implications, is composed of a hydrophilic sugar moiety intricately linked to a hydrophobic …
implications, is composed of a hydrophilic sugar moiety intricately linked to a hydrophobic …
Voacanga globosa Spirobisindole Alkaloids Exert Antiviral Activity in HIV Latently Infected Cell Lines by Targeting the NF-κB Cascade: In Vitro and In Silico …
MSM de Jesus, APG Macabeo, JDA Ramos… - Molecules, 2022 - mdpi.com
Since the efficiency in the transcription of the HIV genome contributes to the success of viral
replication and infectivity, we investigated the downregulating effects of the spirobisindole …
replication and infectivity, we investigated the downregulating effects of the spirobisindole …
The potential of plant systems to break the HIV‐TB link
Tuberculosis (TB) and human immunodeficiency virus (HIV) can place a major burden on
healthcare systems and constitute the main challenges of diagnostic and therapeutic …
healthcare systems and constitute the main challenges of diagnostic and therapeutic …
Anti-HIV crotocascarin ω from Kenyan Croton dichogamus
An anti-HIV methanol-soluble fraction of a 1: 1 CH2Cl2: CH3OH extract of twigs of a Kenyan
Croton dichogamus yielded seven compounds, the new crotocascarin ω (1), the known β …
Croton dichogamus yielded seven compounds, the new crotocascarin ω (1), the known β …
Cascarinoids A–C, a Class of Diterpenoid Alkaloids with Unpredicted Conformations from Croton cascarilloides
XH Gao, YS Xu, YY Fan, LS Gan, JP Zuo, JM Yue - Organic letters, 2018 - ACS Publications
Cascarinoids A–C (1–3), a new class of diterpenoid alkaloids with unpredicted
conformations, were isolated and structurally characterized from Croton cascarilloides. It …
conformations, were isolated and structurally characterized from Croton cascarilloides. It …