Structural biology of SARS-CoV-2: open the door for novel therapies

W Yan, Y Zheng, X Zeng, B He, W Cheng - Signal Transduction and …, 2022 - nature.com
Abstract Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the causative
agent of the pandemic disease COVID-19, which is so far without efficacious treatment. The …

Two years into the COVID-19 pandemic: lessons learned

SJR da Silva, JCF do Nascimento… - ACS infectious …, 2022 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …

Delta variant (B. 1.617. 2) of SARS-CoV-2: Mutations, impact, challenges and possible solutions

M Dhawan, A Sharma, N Priyanka… - Human vaccines & …, 2022 - Taylor & Francis
Since commencement of COVID-19 pandemic, several SARS-CoV-2 variants have emerged
amid containment efforts via vaccination. The Delta variant (B. 1.617. 2), discovered in …

An overview of the vaccine platforms to combat COVID-19 with a focus on the subunit vaccines

F Bayani, NS Hashkavaei, S Arjmand, S Rezaei… - Progress in Biophysics …, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging virus that
has caused the recent coronavirus disease (COVID-19) global pandemic. The current …

Global impact of delta plus variant and vaccination

VP Chavda, V Apostolopoulos - Expert Review of Vaccines, 2022 - Taylor & Francis
The coronavirus, like all viruses, has mutated numerous times since it first appeared in
China in late 2019. Throughout the pandemic, a number of variants have surfaced, changing …

Omicron variant of SARS-CoV-2: An Indian perspective of vaccination and management

VP Chavda, P Balar, D Vaghela, HK Solanki… - Vaccines, 2023 - mdpi.com
Omicron variants have highly influenced the entire globe. It has a high rate of
transmissibility, which makes its management tedious. There are various subtypes of …

Is Omicron the end of pandemic or start of a new innings?

S Das, S Samanta, J Banerjee, A Pal, B Giri… - Travel Medicine and …, 2022 - Elsevier
In the middle of November 2021, Omicron (B. 1.1. 529), a novel variant of SARS-CoV-2 was
identified in South Africa. Owing to continuous increasing cases with rapid transmissibility …

Safety and immunogenicity against ancestral, Delta and Omicron virus variants following a booster dose of an inactivated whole-virus COVID-19 vaccine (VLA2001) …

C Taucher, R Lazarus, H Dellago, G Maurer… - Journal of Infection, 2023 - Elsevier
Objectives Booster doses for COVID-19 vaccinations have been shown to amplify the
waning immune response after primary vaccination and to enhance protection against …

SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice

KS Lee, TY Wong, BP Russ, AM Horspool, OA Miller… - Plos one, 2022 - journals.plos.org
The COVID-19 pandemic has been fueled by SARS-CoV-2 novel variants of concern (VOC)
that have increased transmissibility, receptor binding affinity, and other properties that …

A bispecific antibody targeting RBD and S2 potently neutralizes SARS-CoV-2 Omicron and other variants of concern

M Yuan, X Chen, Y Zhu, X Dong, Y Liu, Z Qian… - Journal of …, 2022 - Am Soc Microbiol
Emerging severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) variants,
especially the Omicron variant, have impaired the efficacy of existing vaccines and most …