J Bian, M Dannappel, C Wan, R Firestein - Cells, 2020 - mdpi.com
The Wnt/β-catenin signaling pathway exerts integral roles in embryogenesis and adult homeostasis. Aberrant activation of the pathway is implicated in growth-associated diseases …
S Shang, F Hua, ZW Hu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Wnt/β-catenin signaling is an evolutionarily conserved and versatile pathway that is known to be involved in embryonic development, tissue homeostasis and a wide variety of human …
X Su, J Ma, X Wei, P Cao, D Zhu, W Chang, Z Liu… - Science, 2017 - science.org
In plants, the photosynthetic machinery photosystem II (PSII) consists of a core complex associated with variable numbers of light-harvesting complexes II (LHCIIs). The …
M Kahn - Nature reviews Drug discovery, 2014 - nature.com
WNT–β-catenin signalling is involved in a multitude of developmental processes and the maintenance of adult tissue homeostasis by regulating cell proliferation, differentiation …
T Valenta, G Hausmann, K Basler - The EMBO journal, 2012 - embopress.org
β‐Catenin (Armadillo in Drosophila) is a multitasking and evolutionary conserved molecule that in metazoans exerts a crucial role in a multitude of developmental and homeostatic …
P Polakis - Cold Spring Harbor perspectives in biology, 2012 - cshperspectives.cshlp.org
Aberrant regulation of the Wnt signaling pathway is a prevalent theme in cancer biology. From the earliest observation that Wnt overexpression could lead to malignant …
ME Fernandez-Sanchez, S Barbier, J Whitehead… - Nature, 2015 - nature.com
The tumour microenvironment may contribute to tumorigenesis owing to mechanical forces such as fibrotic stiffness or mechanical pressure caused by the expansion of hyper …
GS Karagiannis, T Poutahidis, SE Erdman… - Molecular cancer …, 2012 - AACR
Neoplastic cells recruit fibroblasts through various growth factors and cytokines. These “cancer-associated fibroblasts”(CAF) actively interact with neoplastic cells and form a …
The spacing of hair in mammals and feathers in birds is one of the most apparent morphological features of the skin. This pattern arises when uniform fields of progenitor cells …