Monocytes are innate immune cells of the mononuclear phagocyte system that have
emerged as important regulators of cancer development and progression. Our …

Monocytes are progenitors to macrophages and a subclass of dendritic cells (monocyte-
derived dendritic cells, MoDCs), but they also act as circulating sensors that respond to …

The roles of tumor-associated macrophages (TAMs) and circulating monocytes in human
cancer are poorly understood. Here, we show that monocyte subpopulation distribution and …

Exosomes serve as a crucial mode of communication between tumor-associated
macrophages (TAMs) and cancer cells. This study attempted to explore the function of M1 …

The accrual of myeloid-derived suppressor cells (MDSCs) represents a major obstacle to
effective immunotherapy in cancer patients, but the mechanisms underlying this process in …

Background Tumor microenvironment (TME) is a complex environment containing tumor
cells, tumor-associated macrophages (TAMs), interstitial cells, and non-cellular components …

Monocytes influence multiple aspects of tumor progression, including antitumor immunity,
angiogenesis, and metastasis, primarily by infiltrating tumors, and differentiating into tumor …

Abstract Background Tumor-associated macrophages (TAMs) in the tumor
microenvironment influence tumor initiation, invasion and metastasis. Several studies have …

Pancreatic cancer is accompanied by a fibrotic reaction that alters interactions between
tumor cells and the stroma to promote tumor progression. Consequently, strategies to target …

Colorectal cancer is the third most common cancer worldwide, with 1.36 million people
diagnosed in 2012. The prognosis of colorectal cancer is better with an earlier diagnosis …