Pioneering studies performed over the past few decades demonstrate links between
epigenetics and type 2 diabetes mellitus (T2DM), the metabolic disorder with the most …

Epigenetics has long been recognized as a significant field in biology and is defined as the
investigation of any alteration in gene expression patterns that is not attributed to changes in …

Emerging evidence emphasizes the strong impact of regulatory genomic elements in
neurodevelopmental processes and the complex pathways of brain disorders. The present …

Introduction: Epigenetics is the study of reversible modifications to chromatin and their
extensive and profound effects on gene regulation. To date, the role of epigenetics in …

Genetic and epigenetic modifications of genes involved in the key regulatory pathways play
a significant role in the pathophysiology and progression of multifactorial diseases. The …

DNA methylation is an epigenetic modification with wide-ranging consequences across the
life of an organism. This modification can be stable, persisting through development despite …

For the past three decades, more than a thousand of genetic studies have been performed
to find out the genetic variants responsible for the risk of asthma. Until now, all of the …

Epigenetic mechanisms may play a central role in mediating phenotypic plasticity, especially
during range expansions, when populations face a suite of novel environmental conditions …

During range expansions, organisms can use epigenetic mechanisms to adjust to conditions
in novel areas by altering gene expression and enabling phenotypic plasticity. Here, we …

Genetic variants in regulatory regions of some miRNAs might be associated with lung
cancer risk and survival. We performed a case-control study including 1341 non-small cell …