Oncologic photodynamic therapy: basic principles, current clinical status and future directions

D Van Straten, V Mashayekhi, HS De Bruijn, S Oliveira… - Cancers, 2017 - mdpi.com
Photodynamic therapy (PDT) is a clinically approved cancer therapy, based on a
photochemical reaction between a light activatable molecule or photosensitizer, light, and …

The evolution of regulated cell death pathways in animals and their evasion by pathogens

B Tummers, DR Green - Physiological reviews, 2022 - journals.physiology.org
The coevolution of host-pathogen interactions underlies many human physiological traits
associated with protection from or susceptibility to infections. Among the mechanisms that …

[HTML][HTML] Dendritic cells as vectors for therapy

J Banchereau, B Schuler-Thurner, AK Palucka… - Cell, 2001 - cell.com
Vaccines against infectious diseases are the success story of immunology. They have
eradicated smallpox and spared countless people from tetanus, measles, polio, and …

Cell biology of antigen processing in vitro and in vivo

ES Trombetta, I Mellman - Annu. Rev. Immunol., 2005 - annualreviews.org
▪ Abstract The conversion of exogenous and endogenous proteins into immunogenic
peptides recognized by T lymphocytes involves a series of proteolytic and other enzymatic …

Whole tumor antigen vaccines: where are we?

CLL Chiang, G Coukos, LE Kandalaft - Vaccines, 2015 - mdpi.com
With its vast amount of uncharacterized and characterized T cell epitopes available for
activating CD4+ T helper and CD8+ cytotoxic lymphocytes simultaneously, whole tumor …

Toll-dependent selection of microbial antigens for presentation by dendritic cells

JM Blander, R Medzhitov - Nature, 2006 - nature.com
Dendritic cells constitutively sample the tissue microenvironment and phagocytose both
microbial and host apoptotic cells,,,. This leads to the induction of immunity against invading …

Phagocytosis and innate immunity

S Greenberg, S Grinstein - Current opinion in immunology, 2002 - Elsevier
Phagocytosis is an evolutionarily conserved process utilized by many cells to ingest
microbial pathogens, and apoptotic and necrotic corpses. Recent investigation has revealed …

The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells

A Engering, TBH Geijtenbeek, SJ van Vliet… - The Journal of …, 2002 - journals.aai.org
Abstract Dendritic cells (DCs) capture Ags or viruses in peripheral tissue to transport them to
lymphoid organs to induce cellular T cell responses. Recently, a DC-specific C-type lectin …

Scavenger receptors in innate immunity

L Peiser, S Mukhopadhyay, S Gordon - Current opinion in immunology, 2002 - Elsevier
Scavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells)
and certain endothelial cells. They play an important role in uptake and clearance of effete …

Apoptosis facilitates antigen presentation to T lymphocytes through MHC-I and CD1 in tuberculosis

UE Schaible, F Winau, PA Sieling, K Fischer… - Nature medicine, 2003 - nature.com
Protective immunity against Mycobacterium tuberculosis involves major histocompatibility
complex class I (MHC-I)-and CD1-restricted CD8 T cells, but the mechanisms underlying …