Infants who are exclusively breastfed in the first six months of age receive adequate
nutrients, achieving optimal immune protection and growth. In addition to the known …

Small non-coding RNAs including microRNAs (miRNAs) have been recently recognized as
important regulators of gene expression. MicroRNAs play myriads of roles in physiological …

Environmental exposures to hazardous chemicals are associated with a variety of human
diseases and disorders, including cancers. Phase I metabolic activation and detoxification …

Accumulating evidence has demonstrated that genome-derived noncoding RNAs (ncRNAs)
play important roles in modulating inter-individual variations observed in drug metabolism …

Abstract Cytochrome P450 1A2 (CYP1A2) is one of the most abundant and important drug
metabolizing enzymes in human liver. However, little is known about the post-transcriptional …

Introduction: Understanding the factors causing inter-and intra-individual differences in drug
metabolism potencies is required for the practice of personalized or precision medicine, as …

Abstract Cytochrome P450 2D6 (CYP2D6) participates in the metabolism of approximately
20–25% of prescribed drugs. Genetic polymorphisms influence the expression and/or …

Abstract Matrix metalloproteinase‑1 (MMP1) participates in the metastasis of pancreatic
cancer, and its expression can be regulated by endogenous microRNAs (miRs/miRNAs) …

Acetaminophen (APAP) overdose is the leading cause of acute liver failure. Yet the
mechanisms underlying adaptive tolerance toward APAP-induced liver injury are not fully …

This study aimed to identify genetic biomarkers in pancreatic cancer (PC) and explore its
function in PC via a feature-base analysis of bioinformatics. OMIM and DisGeNET databases …