The chemical species involved in H2S signaling remain elusive despite the profound and
pleiotropic physiological effects elicited by this molecule. The dominant candidate …

Molybdenum is the only second-row transition metal required by most living organisms, and
is nearly universally distributed in biology. Enzymes containing molybdenum in their active …

Cysteine hydropersulfide (CysSSH) occurs in abundant quantities in various organisms, yet
little is known about its biosynthesis and physiological functions. Extensive persulfide …

Two decades ago, theoretical model calculations played a truly minor role in understanding
mechanisms of redox-active metalloenzymes. The methods available to treat transition …

Hydrogen sulfide (H 2 S) is an endogenously generated and putative signaling/effector
molecule. Despite its numerous reported functions, the chemistry by which it elicits its …

Abstract Significance: Hydrogen sulfide (H2S), produced by the desulfuration of cysteine or
homocysteine, functions as a signaling molecule in an array of physiological processes …

The chemical biology of thiols (RSH, eg, cysteine and cysteine‐containing
proteins/peptides) has been a topic of extreme interest for many decades due to their …

Molybdenum is widely available to biological systems due to the solubility of its high-valent
oxides in water and is found in two basic forms: as an integral component of the multinuclear …

Xanthine oxidoreductase (XOR) is a complex molybdoflavoenzyme, present in milk and
many other tissues, which has been studied for over 100 years. While it is generally …

Following nitric oxide (nitrogen monoxide) and carbon monoxide, hydrogen sulfide (or its
newer systematic name sulfane, H 2 S) became the third small molecule that can be both …