Platinum (IV) and platinum (II) anticancer complexes with biologically active releasable ligands
P Štarha, R Křikavová - Coordination Chemistry Reviews, 2024 - Elsevier
The concept of multi-action octahedral platinum (IV) complexes is based on the rational
derivatization of anticancer square-planar platinum (II) compounds (eg, cisplatin or …
derivatization of anticancer square-planar platinum (II) compounds (eg, cisplatin or …
Combination of DNA damage, autophagy, and ERK inhibition: novel evodiamine-inspired multi-action Pt (IV) prodrugs with high-efficiency and low-toxicity antitumor …
XM Liu, Z Li, XR Xie, JQ Wang, X Qiao… - Journal of Medicinal …, 2023 - ACS Publications
Exploring multi-targeting chemotherapeutants with advantages over single-targeting agents
and drug combinations is of great significance in drug discovery. Herein, we employed …
and drug combinations is of great significance in drug discovery. Herein, we employed …
Current Status of Novel Multifunctional Targeted Pt (IV) Compounds and Their Reductive Release Properties
L Xu, X Kong, X Li, B Zhang, Y Deng, J Wang, C Duan… - Molecules, 2024 - mdpi.com
Platinum-based drugs are widely used in chemotherapy for various types of cancer and are
considered crucial. Tetravalent platinum (Pt (IV)) compounds have gained significant …
considered crucial. Tetravalent platinum (Pt (IV)) compounds have gained significant …
Exploring paclitaxel-loaded adenosine-conjugated PEGylated PLGA nanoparticles for targeting triple-negative breast cancer
In present investigation, we developed paclitaxel (PTX)-loaded adenosine (ADN)-
conjugated PLGA nanoparticles for combating triple-negative breast cancer (TNBC), where …
conjugated PLGA nanoparticles for combating triple-negative breast cancer (TNBC), where …
Enhancing anti-cancer potential by delivering synergistic drug combinations via phenylboronic acid modified PLGA nanoparticles through ferroptosis-based therapy
In this study, we investigated the potential of the sorafenib (SOR) and simvastatin (SIM)
combination to induce ferroptosis-mediated cancer therapy. To enhance targeted drug …
combination to induce ferroptosis-mediated cancer therapy. To enhance targeted drug …
Synergistic chemotherapy/photothermal therapy for cancer treatment using a co-delivery system of cisplatin and novel conjugated polymers
Y Di, H Zhang, Z Luo, C Feng, X Zhang, S Yang… - Polymer …, 2024 - pubs.rsc.org
In tumor treatment, traditional single therapies such as chemotherapy or photothermal
therapy often suppress tumor growth while also causing serious toxic side effects on normal …
therapy often suppress tumor growth while also causing serious toxic side effects on normal …
Bifunctional Oxaliplatin (IV) Prodrug Based pH-Sensitive PEGylated Liposomes for Synergistic Anticancer Action Against Triple Negative Breast cancer
Triple negative breast cancer (TNBC) exhibits higher susceptibility towards oxaliplatin (OXA)
due to a faulty DNA damage repair system. However, the unfavorable physicochemical …
due to a faulty DNA damage repair system. However, the unfavorable physicochemical …
[PDF][PDF] Deanship of Graduate Studies Al–Quds University
HIA Damdoum - dspace.alquds.edu
Deanship of Graduate Studies Al – Quds University Design, Synthesis and In Vitro Studies of
Lipophilic Mixed Aliphatic/Aromat Page 1 Deanship of Graduate Studies Al – Quds University …
Lipophilic Mixed Aliphatic/Aromat Page 1 Deanship of Graduate Studies Al – Quds University …