Ergosterol is an essential component of fungal cell membranes that determines the fluidity,
permeability and activity of membrane-associated proteins. Ergosterol biosynthesis is a …

Iron overload is a risk factor for diabetes. The link between iron and diabetes was first
recognized in pathologic conditions—hereditary hemochromatosis and thalassemia—but …

Bacteriostatic and bactericidal antibiotic treatments result in two fundamentally different
phenotypic outcomes—the inhibition of bacterial growth or, alternatively, cell death. Most …

Metabolically dormant bacteria present a critical challenge to effective antimicrobial therapy
because these bacteria are genetically susceptible to antibiotic treatment but phenotypically …

Metal nanoparticles used as antifungals have increased the occurrence of fungal–metal
interactions. However, there is a lack of knowledge about how these interactions cause …

Eukaryotic cells contain numerous iron-requiring proteins such as iron-sulfur (Fe-S) cluster
proteins, hemoproteins and ribonucleotide reductases (RNRs). These proteins utilize iron as …

Iron overload is associated with increased diabetes risk. We therefore investigated the effect
of iron on adiponectin, an insulin-sensitizing adipokine that is decreased in diabetic patients …

All living organisms require nutrient minerals for growth and have developed mechanisms to
acquire, utilize, and store nutrient minerals effectively. In the aqueous cellular environment …

Ergosterol, an important component of the fungal cell membrane, is not only essential for
fungal growth and development but also very important for adaptation to stress in fungi …

Transition metal ions are essential nutrients to all forms of life. Iron, copper, zinc,
manganese, cobalt and nickel all have unique chemical and physical properties that make …