Canonical and extra‐telomeric functions of telomerase: Implications for healthy ageing conferred by endurance training

J Denham - Aging Cell, 2023 - Wiley Online Library
Telomerase preserves genomic integrity by maintaining and protecting the telomeres.
Seminal findings from 1985 revealed the canonical role of telomerase and motivated …

Interactions between Schwann cell and extracellular matrix in peripheral nerve regeneration

M Jiang, M Chen, N Liu - Frontiers in Neurology, 2024 - frontiersin.org
Peripheral nerve injuries, caused by various reasons, often lead to severe sensory, motor,
and autonomic dysfunction or permanent disability, posing a challenging problem in …

Graphene oxide-doped chiral dextro-hydrogel promotes peripheral nerve repair through M2 polarization of macrophages

W Deng, X Li, Y Li, Z Huang, Y Wang, N Mu… - Colloids and Surfaces B …, 2024 - Elsevier
Dextro-chirality is reported to specifically promote the proliferation and survival of neural
cells. However, applying this unique performance to nerve repair remains a great challenge …

Chitosan‐Modified Hydrogel Microsphere Encapsulating Zinc‐Doped Bioactive Glasses for Spinal Cord Injury Repair by Suppressing Inflammation and Promoting …

X Su, C Gu, Z Wei, Y Sun, C Zhu… - Advanced Healthcare …, 2025 - Wiley Online Library
Spinal cord injury (SCI) is a common nerve injury caused by external force, resulting in
sensory and motor impairments. Previous studies demonstrated that inhibiting the …

[HTML][HTML] Application of Electrical Stimulation to Enhance Axon Regeneration Following Peripheral Nerve Injury

SS Wariyar, PJ Ward - Bio-protocol, 2023 - ncbi.nlm.nih.gov
Enhancing axon regeneration is a major focus of peripheral nerve injury research. Although
peripheral axons possess a limited ability to regenerate, their functional recovery is very …

A Perspective on Electrical Stimulation and Sympathetic Regeneration in Peripheral Nerve Injuries

T Tian, AM Moore, PA Ghareeb, NM Boulis… - Neurotrauma …, 2024 - liebertpub.com
Peripheral nerve injuries (PNIs) are common and devastating. The current standard of care
relies on the slow and inefficient process of nerve regeneration after surgical intervention …

Conditioning electrical stimulation fails to enhance sympathetic axon regeneration

T Tian, A Harris, J Owyoung, HM SiMa, PJ Ward - bioRxiv, 2023 - biorxiv.org
Peripheral nerve injuries are common, and there is a critical need for the development of
novel therapeutics to complement surgical repair. Conditioning electrical stimulation (CES) …

[HTML][HTML] Fenugreek seed extract combined with acellular nerve allografts promotes peripheral nerve regeneration and neovascularization in sciatic nerve defects

Y Han, Z Liu, C Song - Regenerative Therapy, 2025 - Elsevier
Abstract Background Acellular nerve allografts (ANAs) have been confirmed to improve the
repair and reconstruction of long peripheral nerve defects. However, its efficacy is not …

Long Non-coding RNAs Influence Aging Process of Sciatic Nerves in SD Rats

R Kuang, Y Zhang, G Wu, Z Zhu, S Xu… - … Chemistry & High …, 2024 - ingentaconnect.com
Objectives: To investigate the long non-coding RNAs (lncRNAs) changes in the sciatic nerve
(SN) in Sprague Dawley (SD) rats during aging. Methods: Eighteen healthy SD rats were …

Mesencephalic astrocyte-derived neurotrophic factor promotes axonal regeneration and the motor function recovery after sciatic nerve injury

H Lee, S Jeong, HJ Kim, YG Chung… - … and Biophysical Research …, 2023 - Elsevier
Peripheral nerve injuries have common clinical problems that are often accompanied by
sensory and motor dysfunction and failure of axonal regeneration. Although various …