Exploring the potential function of trace elements in human health: a therapeutic perspective

MR Islam, S Akash, MH Jony, MN Alam… - Molecular and Cellular …, 2023 - Springer
A trace element, known as a minor element, is a chemical element whose concentration is
very low. They are divided into essential and non-essential classes. Numerous physiological …

The role of natural and semi-synthetic compounds in ovarian cancer: Updates on mechanisms of action, current trends and perspectives

MR Islam, MM Rahman, PS Dhar, FT Nowrin… - Molecules, 2023 - mdpi.com
Ovarian cancer represents a major health concern for the female population: there is no
obvious cause, it is frequently misdiagnosed, and it is characterized by a poor prognosis …

A new class of anti-proliferative activity and apoptotic inducer with molecular docking studies for a novel of 1, 3-dithiolo [4, 5-b] quinoxaline derivatives hybrid with a …

MA Ismail, MS Abusaif, MSA El-Gaby, YA Ammar… - RSC …, 2023 - pubs.rsc.org
A new series of 6-(pyrrolidin-1-ylsulfonyl)-[1, 3] dithiolo [4, 5-b] quinoxaline-2-ylidines 10a–f,
12, 14, 16, and 18 were designed, synthesized, and evaluated for their in vitro anticancer …

[HTML][HTML] Spectroscopic and in silico evaluation on the interactive behavior between substituted β-2, 3-dihydrofuran naphthoquinones and human serum albumin

OA Chaves, CHC dos Santos Oliveira… - Chemical Physics …, 2024 - Elsevier
The interactive profile between human serum albumin (HSA, the main carrier of endogenous
and exogenous compounds in the human bloodstream) and five potential anticandidal …

Phytochemical profiling and cytotoxic potential of Arnebia nobilis root extracts against hepatocellular carcinoma using in-vitro and in-silico approaches

A Kiran, A Altaf, M Sarwar, A Malik, T Maqbool, Q Ali - Scientific Reports, 2023 - nature.com
Hepatocellular carcinoma is the fifth most prevalent cancer worldwide. The emergence of
drug resistance and other adverse effects in available anticancer options are challenging to …

Single-cell transcriptome and pigment biochemistry analysis reveals the potential for the high nutritional and medicinal value of purple sea cucumbers

L Xing, L Wang, S Liu, L Sun, GM Wessel… - International Journal of …, 2023 - mdpi.com
The sea cucumber Apostichopus japonicus has important nutritional and medicinal value.
Unfortunately, we know little of the source of active chemicals in this animal, but the plentiful …

Structural and pharmacological diversity of 1, 4-naphthoquinone glycosides in recent 20 years

X Shen, X Liang, C He, L Yin, F Xu, H Li, H Tang… - Bioorganic …, 2023 - Elsevier
naphthoquinones are the most widespread naphthoquinone compounds. Recently, many 1,
4-naphthoquinone glycosides with different structural features have been obtained from both …

[HTML][HTML] Unlocking the potential of 1, 4-naphthoquinones: A comprehensive review of their anticancer properties

E Angulo-Elizari, A Henriquez-Figuereo… - European Journal of …, 2024 - Elsevier
Cancer encompasses a group of pathologies with common characteristics, high incidence,
and prevalence in all countries. Although there are treatments available for this disease …

More than a colour; how pigment influences colourblind microbes

GM Wessel, L Xing, N Oulhen - … Transactions of the …, 2024 - royalsocietypublishing.org
Many animals have pigments when they themselves cannot see colour. Perhaps those
pigments enable the animal to avoid predators, or to attract mates. Maybe even those …

[HTML][HTML] Preclinical evaluation of L-fucoside from lapachol-loaded nanoemulsion as a strategy to breast cancer treatment

SEM Miranda, J de Alcantara Lemos, FM Ottoni… - Biomedicine & …, 2024 - Elsevier
Breast cancer prevails as the most common cancer in women, underscoring an urgent need
for more effective therapies. This study explores the potential of our newly developed …