New and emerging targeted therapies for hidradenitis suppurativa

A Markota Čagalj, B Marinović… - International journal of …, 2022 - mdpi.com
Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease deriving
from the hair follicles. The formation of inflammatory nodules, abscesses, fistulas, and sinus …

Bacterial metabolites: a link between gut microbiota and dermatological diseases

A Stec, M Sikora, M Maciejewska… - International Journal of …, 2023 - mdpi.com
Dysbiosis has been identified in many dermatological conditions (eg, psoriasis, atopic
dermatitis, systemic lupus erythematosus). One of the ways by which the microbiota affect …

A systematic review of Janus kinase inhibitors and spleen tyrosine kinase inhibitors for Hidradenitis suppurativa treatment

A Heidari, Y Ghane, N Heidari, S Sadeghi… - International …, 2024 - Elsevier
Abstract Backgrounds and Aims Hidradenitis suppurativa (HS) is a challenging skin disease
with an underlying inflammatory process. Substantial progress has been made in our …

Neutrophil extracellular traps and neutrophilic dermatosis: an update review

S Li, S Ying, Y Wang, Y Lv, J Qiao, H Fang - Cell Death Discovery, 2024 - nature.com
Neutrophils have both antimicrobial ability and pathogenic effect in the immune system,
neutrophil extracellular traps (NETs) formation is one of the representative behaviors of their …

Single-cell RNA sequencing reveals cellular and transcriptional changes associated with M1 macrophage polarization in hidradenitis suppurativa

P Mariottoni, SW Jiang, CA Prestwood, V Jain… - Frontiers in …, 2021 - frontiersin.org
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease characterized by
recurrent abscesses, nodules, and sinus tracts in areas of high hair follicle and sweat gland …

Short-term effectiveness, safety, and potential predictors of response of secukinumab in patients with severe hidradenitis suppurativa refractory to biologic therapy: a …

P Fernandez-Crehuet, S Haselgruber… - Dermatology and …, 2023 - Springer
Introduction Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease. Biologic
drugs have a key role in the long-term anti-inflammatory treatment of moderate to severe …

Hidradenitis suppurativa

T Jenkins, J Isaac, A Edwards… - Dermatologic Clinics, 2023 - derm.theclinics.com
Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the hair follicles in the
apocrine gland-rich and intertriginous areas of the body. The disease is characterized by …

Innate immunity and microbial dysbiosis in hidradenitis suppurativa–vicious cycle of chronic inflammation

D Chopra, RA Arens, W Amornpairoj… - Frontiers in …, 2022 - frontiersin.org
Hidradenitis Suppurativa (HS) is a chronic multifactorial inflammatory skin disease with
incompletely understood mechanisms of disease pathology. HS is characterized by aberrant …

[HTML][HTML] Hidradenitis suppurativa and follicular occlusion syndrome: where is the pathogenetic link?

B Jastrząb, JC Szepietowski, Ł Matusiak - Clinics in Dermatology, 2023 - Elsevier
The follicular occlusion tetrad complex encompasses several entities (hidradenitis
suppurativa, acne conglobata, dissecting cellulitis of the scalp, and pilonidal cyst) that share …

The composition of subgingival microbiome in hidradenitis suppurativa and periodontitis patients

B Jastrząb, B Paśnik-Chwalik, K Dębska-Łasut… - Pathogens, 2023 - mdpi.com
Hidradenitis suppurativa (HS) is a chronic inflammatory disorder of the pilosebaceous unit of
the intertriginous body areas. Recent findings have suggested the association between …