Green chemistry approaches for thiazole containing compounds as a potential scaffold for cancer therapy

D Sharma, V Sharma, A Sharma, R Goyal… - Sustainable Chemistry …, 2021 - Elsevier
The exhaustive exploration of the conventional synthetic approaches for the synthesis of
nitrogen and sulphur containing heterocyclic moieties has diverted the attention of …

Application of phenacyl bromide analogs as a versatile organic intermediate for the synthesis of heterocyclic compounds via multicomponent reactions

R Javahershenas - Molecular Diversity, 2023 - Springer
Due to the increased interest in heterocyclic compounds over the past decade, many
pharmaceutical and organic chemists have explored the synthesis of various materials …

Microwave irradiated one pot, three component synthesis of a new series of hybrid coumarin based thiazoles: Antibacterial evaluation and molecular docking studies

S Mamidala, SR Peddi, RK Aravilli, PC Jilloju… - Journal of Molecular …, 2021 - Elsevier
A series of new coumarin based thiazoles were synthesized by the microwave irradiation of
thiocarbohydrazide, aldehydes and 3-(2-bromoacetyl) coumarins. Structures of all the …

Novel thiazole-based cyanoacrylamide derivatives: DNA cleavage, DNA/BSA binding properties and their anticancer behaviour against colon and breast cancer cells

K Barakat, MA Ragheb, MH Soliman, AM Abdelmoniem… - BMC chemistry, 2024 - Springer
A novel series of 2-cyano-3-(pyrazol-4-yl)-N-(thiazol-2-yl) acrylamide derivatives (3a–f) were
synthesized using Knoevenagel condensation and characterized using various spectral …

Novel Mononuclear Cu (II), Ni (II), and Co (II) Complexes of Coumarinyl‐Pyrazolyl‐Thiazole Thiosemicarbazone: Synthesis, Characterization, and Biological …

M Shebl, TE Ali, MA Assiri - Applied Organometallic Chemistry, 2025 - Wiley Online Library
ABSTRACT Cu (II), Ni (II), and Co (II) acetates reacted with a thiosemicarbazone ligand
(CPPTSC; HL) to produce novel solid complexes with the general formula [M (L)(H2O) m] …

A facile one-pot, three component synthesis of a new series of 1, 3, 4-thiadiazines: Anticancer evaluation and molecular docking studies

S Mamidala, V Vangala, SR Peddi… - Journal of Molecular …, 2021 - Elsevier
Abstract A series of new 1, 3, 4-thiadiazines were synthesized by the conventional method of
dehydroacetic acid, thiocarbohydrazide and substituted phenacyl bromides or substituted 3 …

A facile one-pot, three-component synthesis of a new series of thiazolyl pyrazole carbaldehydes: In vitro anticancer evaluation, in silico ADME/T, and molecular …

S Mamidala, RK Aravilli, G Ramesh, S Khajavali… - Journal of Molecular …, 2021 - Elsevier
A series of thiazolyl pyrazole carbaldehydes (4a-n) were synthesized by conventional
method using thiosemicarbazide, substituted phenacyl bromides, substituted 3 …

Exploring the Potential of Substituted 4-Thiazolidinone Derivatives in the Treatment of Breast Cancer: Synthesis, Biological Screening and In Silico Studies

G Teli, P Sharma, PA Chawla - Polycyclic Aromatic Compounds, 2023 - Taylor & Francis
A series of 4-thiazolidinone conjugates bearing quinoline/indole/furan scaffolds were
designed as potential anti-breast cancer agents, synthesized, and investigated for their anti …

Green synthesis of thiazole bis-imines as fluorometric sensor for determination of lead in environmental, biological, and food samples

CR da Silva Oliveira, WT Suarez… - … Acta Part A: Molecular …, 2025 - Elsevier
In this work, we describe for the first time the synthesis of a thiazole bis-imine fluorometric
sensor for the selective determination of Pb 2+ in environmental, biological, and food …

Thiazole derivatives: prospectives and biological applications

U Fathy - Journal of Sulfur Chemistry, 2024 - Taylor & Francis
Thiazole derivatives have long been a hot topic in pharmaceutical research and remain
among the greatest active fields in heterocyclic chemistry. Thiazole derivatives, as one of the …